ANTI-CHROMOBOX PROTEIN HOMOLOG 1
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- CAS-Nr.
- Englisch Name:
- ANTI-CHROMOBOX PROTEIN HOMOLOG 1
- Synonyma:
- Anti-CBX;Anti-M31;Anti-P20;Anti-MRS;Anti-p25β;Anti-NGAL;Anti-MOD1;Anti-24p3;Anti-TPPP1;Anti-DFNB2
- CBNumber:
- CB2367028
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-CHROMOBOX PROTEIN HOMOLOG 1 Eigenschaften
- storage temp.
- −20°C
- Aggregatzustand
- buffered aqueous solution
- Biologische Quelle
- rabbit
ANTI-CHROMOBOX PROTEIN HOMOLOG 1 Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer′s disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer′s disease. (provided by RefSeq)
ANTI-CHROMOBOX PROTEIN HOMOLOG 1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-CHROMOBOX PROTEIN HOMOLOG 1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 12)Lieferanten
- Monoclonal Anti-CDK5R1 antibody produced in mouse
- Anti-TPPP3 antibody produced in rabbit
- Anti-TPPP3, (N-terminal) antibody produced in rabbit
- Anti-LCN2 antibody produced in rabbit
- Monoclonal Anti-CBX5 antibody produced in mouse
- Anti-TPPP (166-180) antibody produced in rabbit
- Anti-TPPP antibody produced in rabbit
- Anti-DCTN5 antibody produced in rabbit
- Monoclonal Anti-MYO7A antibody produced in mouse
- Anti-TPPP (16-30) antibody produced in rabbit
- Anti-TPPP antibody produced in mouse
- Anti-CBX1, (N-terminal) antibody produced in rabbit
- Monoclonal Anti-DEFA1 antibody produced in mouse
- Anti-MYO7A antibody produced in rabbit
- Anti-Lipocalin 2/NGAL (AB2) antibody produced in goat
- Anti-CBX1/HP1-β antibody produced in goat
- ANTI-CHROMOBOX PROTEIN HOMOLOG 1
- ANTI-HETEROCHROMATIN PROTEIN 1 HOMOLOG BETA
- ANTI-HETEROCHROMATIN PROTEIN P25
- ANTI-HP1HSBETA
- ANTI-HP1-BETA
- ANTI-MODIFIER PROTEIN M31
- ANTI-P25BETA
- Anti-Chromobox Protein Homolog 1, Anti-Heterochromatin Protein 1 Homolog β, Anti-Heterochromatin Protein p25, Anti-HP1Hsβ, Anti-Modifier Protein M31, Anti-p25β
- Anti-p25β
- Anti-HP1Hsβ
- Anti-p25alpha
- Anti-TPPP/p25
- Anti-TPPP1
- Anti-Lipocalin-2
- Anti-Neutrophil gelatinase-associated lipocalin precursor
- Anti-NGAL
- Anti-25 kDa alpha-2-microglobulin-related subunit of MMP-9
- Anti-Oncogene 24p3
- Anti-CBX
- Anti-DFNA11
- Anti-DFNB2
- Anti-HP1-β
- Anti-M31
- Anti-NSRD2
- Anti-USH1B
- Anti-MOD1
- Anti-Tubulin polymerization promoting protein
- Anti-Dynactin 5 (p25)
- Anti-Mgc3248
- Anti-Tubulin polymerization-promoting protein family member 3
- Anti-CGI-38
- Anti-P20
- Anti-defensin, alpha 1, myeloid-related sequence
- Anti-MRS
- Anti-HP1Hsalpha
- Anti-chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- Anti-MYU7A
- Anti-p25gamma
- Anti-MGC138393
- Anti-24p3
- Anti-AW212229
- Anti-HGNC:1551
