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Budipin

BUDIPINE Struktur
57982-78-2
CAS-Nr.
57982-78-2
Bezeichnung:
Budipin
Englisch Name:
BUDIPINE
Synonyma:
budipin;BUDIPINE;BUDIPINE USP/EP/BP;BUDIPINE(FORR&DONLY);Budipine, 10 mM in DMSO;4,4-diphenyl-1-tert-butyl-piperidine;1-TERT-BUTYL-4,4-DIPHENYL-PIPERIDINE;1-(1,1-dimethylethyl)-4,4-diphenylpiperidine;1-(1,1-dimethylethyl)-4,4-diphenyl-piperidin;Piperidine,1-(1,1-dimethylethyl)-4,4-diphenyl-
CBNumber:
CB2369325
Summenformel:
C21H27N
Molgewicht:
293.45
MOL-Datei:
57982-78-2.mol

Budipin Eigenschaften

Schmelzpunkt:
108.5°C
Siedepunkt:
425.29°C (rough estimate)
Dichte
0.9665 (rough estimate)
Brechungsindex
1.4900 (estimate)
storage temp. 
2-8°C
L?slichkeit
DMSO : 25 mg/mL (85.19 mM; Need ultrasonic)
Aggregatzustand
Solid
pka
10.36±0.10(Predicted)
Farbe
Light yellow to khaki
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H332 Gesundheitssch?dlich bei Einatmen. Akute Toxizit?t inhalativ Kategorie 4 Warnung P261, P271, P304+P340, P312
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P310 Sofort GIFTINFORMATIONSZENTRUM/Arzt/ anrufen.

Budipin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Parkinsan was launched in Germany as a centrally-active anti-Parkinsonian agent. It can be prepared in three steps: a Mannich-aldol sequence to assemble the 4-phenylpiperidine scaffold followed by a Friedel-Crafts reaction to introduce the second phenyl ring. Parkinsan is effective for the treatment of Parkinsonian tremors and is similar in action to, but more potent than, biperiden. It exhibits use-dependent, open channel, uncompetitive NMDA receptor antagonistic activity. This may occur by binding to the PCP site in addition to interacting with sigma, binding sites in the frontal cortex. Parkinsan is also an antagonist at presynaptic muscarinic autoreceptors but facilitation of direct or indirect dopaminergic transmission does not contribute to its actions. While its mechanism of action is not completely understood, it has a weak inhibitory effect on dopamine reuptake, inhibits evoked GABA release (with low affinity for GABA-A receptors and a lower affinity for benzodiazepine receptors), and has a weak inhibitory effect on MAO-B.

Budipin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Budipin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 63)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29792 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 20581 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39039 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501
product@acmec-e.com China 33324 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58

57982-78-2(Budipin)Verwandte Suche:


  • BUDIPINE
  • 1-(1,1-dimethylethyl)-4,4-diphenyl-piperidin
  • 1-(1,1-dimethylethyl)-4,4-diphenylpiperidine
  • budipin
  • 1-TERT-BUTYL-4,4-DIPHENYL-PIPERIDINE
  • BUDIPINE(FORR&DONLY)
  • 4,4-diphenyl-1-tert-butyl-piperidine
  • Piperidine,1-(1,1-dimethylethyl)-4,4-diphenyl-
  • BUDIPINE USP/EP/BP
  • monoamine oxidase type B (MAO-B),inhibit,CNS disorders,Parkinson disease,Budipine,Inhibitor,dopaminergic
  • Budipine, 10 mM in DMSO
  • 57982-78-2
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