DENDROTOXIN-K Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Dendrotoxin-K is suitable for use as a potassium voltage-gated channel subfamily A member 1 (Kv1.1) channel blocker in axon and human embryonic kidney (HEK293) cells. It has also been used as a selective blocker of Kv channels in mice.

Biochem/physiol Actions

Dendrotoxin-K (DTXk) is isolated from mamba snake Dendroaspis polylepis and interacts with the β-turn region in the N-terminal sequence of the potassium channel. It inhibits tumor progression in gefitinib-resistant non-small cell lung cancer cells. DTXk induces neuronal damage in the hippocampus via N-methyl-d-aspartate (NMDA) and non-NMDA receptors.

DENDROTOXIN-K Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

DENDROTOXIN-K Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

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• DENDROTOXIN-K
• Voltage-gated Ion Channels
• Ion Channels
• Potassium Channel Modulators
• Monovalent Ion Channels
• BioChemical
• Cell Signaling and Neuroscience
• Cell Biology
• Monovalent Ion Channels
• Potassium Channel Modulators
• Voltage-gated Ion Channels