PROSTAGLANDIN D2
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- CAS-Nr.
- 41598-07-6
- Englisch Name:
- PROSTAGLANDIN D2
- Synonyma:
- PGD2;PGDS;Prostaglandin D?;PROSTAGLANDIN D2;PROSTAGLANDINS D2;2PROSTAGLANDIN D2;PGD2 (Prostaglandin D2);RP23-47P18.11-006, 21kDa;Prostaglandin D2;11-dehydroprostaglandinf2-alpha
- CBNumber:
- CB2433095
- Summenformel:
- C20H32O5
- Molgewicht:
- 352.47
- MOL-Datei:
- 41598-07-6.mol
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PROSTAGLANDIN D2 Eigenschaften
- Schmelzpunkt:
- 68°C
- Siedepunkt:
- 406.07°C (rough estimate)
- alpha
- +7.5°(D/21℃)(c=1,THF)
- Dichte
- 1.0601 (rough estimate)
- Brechungsindex
- 1.6120 (estimate)
- storage temp.
- -20°C
- L?slichkeit
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly), THF (Slightly)
- pka
- 4.76±0.10(Predicted)
- Aggregatzustand
- White solid
- Farbe
- White to Light Orange
- Biologische Quelle
- synthetic
- BRN
- 2170623
- Stabilit?t:
- Light Sensitive
- InChIKey
- BHMBVRSPMRCCGG-OUTUXVNYSA-N
- SMILES
- [H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)CC(=O)[C@]1([H])\C=C\[C@@H](O)CCCCC
PROSTAGLANDIN D2 Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R60:Kann die Fortpflanzungsf?higkeit beeintr?chtigen.
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Prostaglandin D
2 (PGD
2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD
2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD
2 is also produced in the brain
via an alternative pathway involving a soluble, secreted PGD-
synthase also known as β-
trace. In the brain, PGD
2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD
2 inhibits human ovarian tumor cell proliferation with an IC
50 of 6.8 μM.
Verwenden
Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.
Definition
ChEBI: A member of the class of prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- s
ereoisomer).
PROSTAGLANDIN D2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-oxo-, (5Z,9α,13E,15S)- (9CI)
Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-hydroxy-, (5Z,9α,11α,13E,15S)- (9CI)
Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-hydroxy-, methyl ester, (5Z,9α,11α,13E,15S)- (9CI)
Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (5Z,9α,11α,13E,15S)- (9CI)
Prosta-5,13-dien-1-oic acid, 15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-9-hydroxy-11-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (5Z,9α,11α,13E,15S)- (9CI)
5-Heptynoic acid, 7-oxo-, methyl ester
2H-Pyran, tetrahydro-2-[[(1S)-1-[(1E)-2-iodoethenyl]hexyl]oxy]-
(4R)-(+)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE
Downstream Produkte
PROSTAGLANDIN D2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 93)Lieferanten
41598-07-6()Verwandte Suche:
- 9,15-dihydroxy-11-oxo-,(5z,9-alpha,13e,15s)-prosta-13-dien-1-oicacid
- prostaglandin D2 cell culture tested
- prostaglandind2synthetichygroscopic
- (5z,9α,13e,15s)-9,15-dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid
- 7-[(1R,2R,5S)-5-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid
- PGD2, (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid
- (5Z,13E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid
- Prostaglandin D2,(5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid, PGD2
- Prostaglandin D2 Lipid Maps MS Standard
- (Z)-7-((1R,2R,5S)-5-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-3-oxocyclopentyl)hept-5-enoic acid
- Anti-Ptgds antibody produced in goat
- PGDS
- prostaglandin D2 synthase (brain)
- RP23-47P18.11-006, 21kDa
- PGD2 (Prostaglandin D2)
- Prostaglandin D?
- PROSTAGLANDIN D2
- PROSTAGLANDINS D2
- 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID
- [5Z,9ALPHA,13E,15S]9,15-DIHYDROXY-11-OXOPROSTA-5,13-DIEN-1-OIC ACID
- 11-dehydroprostaglandinf2-alpha
- Prostaglandin D2 MaxSpecStandard
- Prostaglandin D - CAS 41598-07-6 - Calbiochem
- Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)-
- Prostaglandin D2, HDP1 and CRTH2 receptor agonist
- Prostaglandin D2
- PGD2
- 2PROSTAGLANDIN D2
- 41598-07-6
- Fatty Acids
- Prostaglandins
- Lipids
- BioChemical
- Biochemicals and Reagents
