BROMOENOL LACTONE
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- CAS-Nr.
- 88070-98-8
- Englisch Name:
- BROMOENOL LACTONE
- Synonyma:
- BEL;HELSS;HALOENOL LACTONE;BROMOENOL LACTONE;(6E)-Bromoenol lactone;Bromoenol lactone (BEL);Bromoenol Lactone Solution;HALOENOL LACTONE SUICIDE SUBSTRATE;HELSS, inhibitor of Ca2+ independent PLA2;(6E)-6-(bromomethylidene)-3-naphthalen-1-yloxan-2-one
- CBNumber:
- CB2471725
- Summenformel:
- C16H13BrO2
- Molgewicht:
- 317.18
- MOL-Datei:
- 88070-98-8.mol
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BROMOENOL LACTONE Eigenschaften
- Schmelzpunkt:
- 103-106℃
- Siedepunkt:
- 467.0±45.0 °C(Predicted)
- Dichte
- 1.538±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.soluble
- Aggregatzustand
- White solid.
- Farbe
- White to yellow
- Biologische Quelle
- synthetic (organic)
- maximale Wellenl?nge (λmax)
- 224 nm
- InChI
- 1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
- InChIKey
- BYUCSFWXCMTYOI-ZRDIBKRKSA-N
- SMILES
- [H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23
BROMOENOL LACTONE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Verwenden
HELSS (Haloenol lactone suicide substrate, BEL, Bromoenol lactone) is an inhibitor of Ca-independent PLA2 and Mg-dependent PAP.
Biochem/physiol Actions
Potent, irreversible inhibitor of calcium-independent phospholipase A2 and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC50 = 8μM); enzyme activated irreversible chymotrypsin inhibitor (Ki = 636 nM).
BROMOENOL LACTONE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
BROMOENOL LACTONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 80)Lieferanten
88070-98-8()Verwandte Suche:
- E-6-(BROMOETHYLENE)TETRAHYDRO-3-(1-NAPHTHYL)-2H-PYRAN-2-ONE
- (E)-6-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPHTHALENYL)-2H-PYRAN-2-ONE
- (E)-6-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPTHALENYL)-2H-PYRAN-2-ONE
- HELSS
- HALOENOL LACTONE
- HALOENOL LACTONE SUICIDE SUBSTRATE
- BEL
- BROMOENOL LACTONE
- 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one
- BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one
- Bromoenol Lactone Solution
- HELSS (Haloenol lactone suicide substrate, BEL, Bromoenol lactone)
- Bromoenol lactone (BEL)
- (6E)-6-(bromomethylidene)-3-naphthalen-1-yloxan-2-one
- (6E)-Bromoenol lactone
- 2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-, (6E)-
- (E)-6-(Bromomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one
- HELSS, inhibitor of Ca2+ independent PLA2
- 88070-98-8
- A to C
- Biochemicals and Reagents
- BioChemical
- Chymotrypsin, alpha-
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- Enzymes, Inhibitors, and Substrates
