Enoximone

77671-31-9

CAS-Nr.: 77671-31-9

Englisch Name:: Enoximone

Synonyma:: Perfan;Pedane;RMI-17043;ENOXIMONE;MDL-17043;Fenoximone;Enoximone USP/EP/BP;Enoximone, 10 mM in DMSO;4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one;1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE

CBNumber:: CB2682723

Summenformel:: C12H12N2O2S

Molgewicht:: 248.3

MOL-Datei:: 77671-31-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 109

Enoximone Eigenschaften

Schmelzpunkt:: 255-258°C

Dichte: 1.33

storage temp.: Sealed in dry,Room Temperature

L?slichkeit: DMSO: 28 mg/mL, soluble

pka: 10.37±0.70(Predicted)

Aggregatzustand: solid

Farbe: light yellow

InChI: 1S/C12H12N2O2S/c1-7-10(14-12(16)13-7)11(15)8-3-5-9(17-2)6-4-8/h3-6H,1-2H3,(H2,13,14,16)

InChIKey: ZJKNESGOIKRXQY-UHFFFAOYSA-N

SMILES: CSc1ccc(cc1)C(=O)C2=C(C)NC(=O)N2

CAS Datenbank: 77671-31-9(CAS DataBase Reference)

Sicherheit

RIDADR	3249
WGK Germany	3
HazardClass	6.1(b)
PackingGroup	III
Speicherklasse	10 - Combustible liquids

Enoximone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Enoximone is a phosphodiesterase inhibitor indicated for selective use as a cardiostimulant in heart transplant patient maintenance. It is currently being investigated for other indications including acute congestive heart failure.

Verwenden

Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.

Biologische Aktivit?t

Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro .

Enoximone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Nitrosylhydroxid Ethylacetat

Downstream Produkte

Enoximone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 109)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shaanxi Xianhe Biotech Co., Ltd	+86-17709210191; +8617709210191	Jerry@xhobio.com	China	906	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9996	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	027-88013699 17354350817	Ryan@jiutian-bio.com	China	5945	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

77671-31-9()Verwandte Suche:

Methylsalicylat Imidazol Hexamethylphosphorsaeuretriamid 2,6-Dimethyloct-7-en-2-ol Mexiletin 1-Methylimidazol Basic Violet 1 alpha-Toluolsulfonylfluorid Tribenuron methyl Methyl-4-hydroxybenzoat Methylacrylat Methanol Kresoxim-methyl Methyl

ENOXIMONE
2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-
Fenoximone
MDL-17043
Pedane
Perfan
RMI-17043
4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one
1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE
4-Methyl-5-[4-(methylthio)benzoyl]-1,3-dihydro-2H-imidazol-2-one
Enoximone USP/EP/BP
4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one
inhibit,Enoximone,bronchodilatory,CD11b,eosinophils,vasodilating,Phosphodiesterase (PDE),airway,cAMP,PDE3,PDE4A,Inhibitor,anti-inflammatory,Antiasthma
Enoximone, 10 mM in DMSO
77671-31-9
BioChemical
Cell Signaling and Neuroscience
G Proteins and Cyclic Nucleotides
Phosphodiesterase Inhibitors
Cyclic Nucleotide Metabolism
Cell Biology
APIs
API

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