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3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid

Rhodamine 123 Struktur
62669-70-9
CAS-Nr.
62669-70-9
Bezeichnung:
3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid
Englisch Name:
Rhodamine 123
Synonyma:
rh123;R 302;R 22420;RHODAMINE 123;-Cellstain-Rh123;Rhodamine 123 ,98%;Rhodamine 123, 99+%;Rhodamine 123, pure;Rhodamine 123 (RH-123;Rhodamine 123 (Green)
CBNumber:
CB2702364
Summenformel:
C21H17ClN2O3
Molgewicht:
380.83
MOL-Datei:
62669-70-9.mol

3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Eigenschaften

Schmelzpunkt:
235 °C
Dichte
1.2224 (rough estimate)
Brechungsindex
1.6500 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
ethanol: 20 mg/mL, clear, red
Aggregatzustand
Powder
Farbe
Red-brown to brown or dark green
Aussehen
brown crystals
Wasserl?slichkeit
Partially soluble
maximale Wellenl?nge (λmax)
501 nm, 507 nm
BRN 
6030951
Stabilit?t:
Hygroscopic
Biologische Anwendungen
Measuring membrane potential; detecting cancer cells,spores,prostate cancer,stress biomarkers; treating disc degenerative disease,epilepsy,erectile dysfunction; apoptosis assays; tumor cell multidrug resistance assay; implantable
Major Application
Colored bubbles; color filters; liquid crystal displays; light-emitting diodes; luminescent materials;nanophotonic composites; paints; semiconductor electrodes;solar cells
InChI
1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H
InChIKey
MYFATKRONKHHQL-UHFFFAOYSA-N
SMILES
Cl[H].COC(=O)c1ccccc1C2=C3C=CC(=N)C=C3Oc4cc(N)ccc24
CAS Datenbank
62669-70-9(CAS DataBase Reference)
EPA chemische Informationen
Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (62669-70-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 22
S-S?tze: 22-24/25
WGK Germany  3
RTECS-Nr. ZE0883000
TSCA  TSCA listed
HS Code  32049010
Speicherklasse 11 - Combustible Solids
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp; also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem cells known as the side population, rhodamine 123 is used to detect this group of stem cells. Rhodamine 123 also accumulates within mitochondria due to its positive charge and can inhibit oxidative phosphorylation. Rhodamine 123 has excitation/emission maxima of 507/529 nm.

Chemische Eigenschaften

red-brown to brown or dark green powder

Verwenden

Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).

3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 343)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+8617392709771
1097@dideu.com China 3992 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040
1056@dideu.com China 3970 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289
contact@trustwe.com China 5745 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
Xi'an MC Biotech, Co., Ltd.
029-89275612 +8618991951683
mcbio_sales@163.com China 2251 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894
shawn@hirisunpharm.com CHINA 9911 58

62669-70-9(3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid)Verwandte Suche:


  • Rhodamine methyl ester hydrochloride
  • Rhodamin 123 Chloride, laser grade
  • 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride
  • Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride
  • Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
  • Rhodamine 123 ,98%
  • RHODAMINE 123, 99+%, PURE
  • Rhodamine 123, pure
  • Rhodamine 123,2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester
  • RhodaMine 123 Chloride, Laser Grade
  • Rhodamine 123, 99+%
  • 2-[6-AMINO-3-IMINO-3H-XANTHEN-9-YL]BENZOIC ACID METHYL ESTER
  • 2-(6-AMINO-3-IMINO-3H-XANTHEN-9-YL)BENZOIC ACID METHYL ESTER CHLORIDE
  • RHODAMINE METHYL ESTER CHLORIDE
  • R 22420
  • R 302
  • Rhodamine 123 Chloride
  • RHODAMINE 123, FOR FLUORESCENCE
  • -Cellstain-Rh123
  • Rhodamine 123, pure, 99+%
  • RHODAMINE 123
  • RHODAMINE 123 HYDROCHLORIDE
  • 2-(6-amino-3-imino-3h-xanthen-9-yl)benzoicacidmethylestermonohydrochlorid
  • 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-xanthyliuchloride
  • 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)xanthyliumchloride
  • benzoicacid,2-(6-amino-3-imino-3h-xanthen-9-yl)-,methylester,monohydroch
  • Rhodamine 123 *CAS 62669-70-9*
  • Rhodamine 123 (RH-123
  • 3,6-DIAMINO-9-[2-(METHOXYCARBONYL)PHENYL]-10???XANTHEN-10-YLIUM CHLORIDE
  • Rhodamine 123 (Green)
  • rh123
  • 62669-70-9
  • C21H17N2O3Cl
  • C28H24N4O10S
  • C21H16N2O3HCl
  • C21H17ClN2O3
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Indicators and Probes
  • Alphabetical
  • Lipophilic and Membrane Probes
  • Biochemicals and Reagents
  • BioChemical
  • Xanthene
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Fluorescent Labels & Indicators
  • ROX
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