3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid
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- CAS-Nr.
- 62669-70-9
- Bezeichnung:
- 3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid
- Englisch Name:
- Rhodamine 123
- Synonyma:
- rh123;R 302;R 22420;RHODAMINE 123;-Cellstain-Rh123;Rhodamine 123 ,98%;Rhodamine 123, 99+%;Rhodamine 123, pure;Rhodamine 123 (RH-123;Rhodamine 123 (Green)
- CBNumber:
- CB2702364
- Summenformel:
- C21H17ClN2O3
- Molgewicht:
- 380.83
- MOL-Datei:
- 62669-70-9.mol
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3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Eigenschaften
- Schmelzpunkt:
- 235 °C
- Dichte
- 1.2224 (rough estimate)
- Brechungsindex
- 1.6500 (estimate)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- L?slichkeit
- ethanol: 20 mg/mL, clear, red
- Aggregatzustand
- Powder
- Farbe
- Red-brown to brown or dark green
- Aussehen
- brown crystals
- Wasserl?slichkeit
- Partially soluble
- maximale Wellenl?nge (λmax)
- 501 nm, 507 nm
- BRN
- 6030951
- Stabilit?t:
- Hygroscopic
- Biologische Anwendungen
- Measuring membrane potential; detecting cancer cells,spores,prostate cancer,stress biomarkers; treating disc degenerative disease,epilepsy,erectile dysfunction; apoptosis assays; tumor cell multidrug resistance assay; implantable
- Major Application
- Colored bubbles; color
filters; liquid crystal displays; light-emitting diodes;
luminescent materials;nanophotonic composites;
paints; semiconductor electrodes;solar cells
- InChI
- 1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H
- InChIKey
- MYFATKRONKHHQL-UHFFFAOYSA-N
- SMILES
- Cl[H].COC(=O)c1ccccc1C2=C3C=CC(=N)C=C3Oc4cc(N)ccc24
- CAS Datenbank
- 62669-70-9(CAS DataBase Reference)
- EPA chemische Informationen
- Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (62669-70-9)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| S-S?tze: |
22-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
ZE0883000 |
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| TSCA |
TSCA listed |
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| HS Code |
32049010 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp; also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem cells known as the side population, rhodamine 123 is used to detect this group of stem cells. Rhodamine 123 also accumulates within mitochondria due to its positive charge and can inhibit oxidative phosphorylation. Rhodamine 123 has excitation/emission maxima of 507/529 nm.
Chemische Eigenschaften
red-brown to brown or dark green powder
Verwenden
Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).
3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 348)Lieferanten
62669-70-9(3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthyliumchlorid)Verwandte Suche:
Ammoniumchlorid
Hydrogen-3,6-bis(diethylamino)-9-(2,4-disulfonatophenyl)xanthylium, Natriumsalz
RHODAMINE 110
9-(2-Carboxyphenyl)-3,6-bis(di-ethylamino)-xanthyliumchlorid
9-(2-(Ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthyliumchlorid
Phenylvalerat
Natriumchlorid
Cholinchlorid
Calciumchlorid
9-(2-Carboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xanthen[2,3,4-ij:5,6,7-i'j']dichinolizin-18-iumchlorid
Kaliumchlorid
Polyvinyl chloride
9-(2-Carboxyphenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthyliumperchlorat
9-(2-Carboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']dichinolizin-18-iumperchlorat
9-(2-Carboxylatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium
9-(2-Carboxyphenyl)-3,6-bis(methylamino)xanthyliumperchlorat
Phenylessigsure
4-(DICYANOMETHYLENE)-2-METHYL-6-(JULOLIDIN-4-YL-VINYL)-4H-PYRAN
- Rhodamine methyl ester hydrochloride
- Rhodamin 123 Chloride, laser grade
- 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monohydrochloride
- Benzoic acid, 2-(6-amino-3-imino-3H-xanthen-9-yl)-, methyl ester, monohydrochloride
- Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
- Rhodamine 123 ,98%
- RHODAMINE 123, 99+%, PURE
- Rhodamine 123, pure
- Rhodamine 123,2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester
- RhodaMine 123 Chloride, Laser Grade
- Rhodamine 123, 99+%
- 2-[6-AMINO-3-IMINO-3H-XANTHEN-9-YL]BENZOIC ACID METHYL ESTER
- 2-(6-AMINO-3-IMINO-3H-XANTHEN-9-YL)BENZOIC ACID METHYL ESTER CHLORIDE
- RHODAMINE METHYL ESTER CHLORIDE
- R 22420
- R 302
- Rhodamine 123 Chloride
- RHODAMINE 123, FOR FLUORESCENCE
- -Cellstain-Rh123
- Rhodamine 123, pure, 99+%
- RHODAMINE 123
- RHODAMINE 123 HYDROCHLORIDE
- 2-(6-amino-3-imino-3h-xanthen-9-yl)benzoicacidmethylestermonohydrochlorid
- 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-xanthyliuchloride
- 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)xanthyliumchloride
- benzoicacid,2-(6-amino-3-imino-3h-xanthen-9-yl)-,methylester,monohydroch
- Rhodamine 123 *CAS 62669-70-9*
- Rhodamine 123 (RH-123
- 3,6-DIAMINO-9-[2-(METHOXYCARBONYL)PHENYL]-10???XANTHEN-10-YLIUM CHLORIDE
- Rhodamine 123 (Green)
- rh123
- 62669-70-9
- C21H17N2O3Cl
- C28H24N4O10S
- C21H16N2O3HCl
- C21H17ClN2O3
- Fluorescent Probes, Labels, Particles and Stains
- Fluorescent Indicators and Probes
- Alphabetical
- Lipophilic and Membrane Probes
- Biochemicals and Reagents
- BioChemical
- Xanthene
- Amines
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Fluorescent Labels & Indicators
- ROX
