ANTI-PHOSPHO-TAU (PSER199/202) Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Anti-phospho-Tau (pSer^199/202) antibody (diluted 1:1000 in PBS containing 0.3% Triton X-100 and 0.5% BSA) can be used in immunocytochemistry for identification of protein aggregates. It can also be used as primary antibody (diluted 1: 3000) in immunohistochemistry.

Allgemeine Beschreibung

Tau proteins are known as microtubule-associated phosphoprotein (MAP) and express mainly in neurons of central nervous system. It has a crucial role in tubulin polymerization and facilitates microtubules assembly and stability. The biological activity of tau proteins depends on degree of its phosphorylation. Anti-phospho-Tau (pSer^199/202) antibody can be used in microarray and western blotting. It can also be used in immunoblotting. Rabbit anti- phospho-Tau (pSer^199/202) antibody reacts specifically with human Tau (pSer^199/202) (45-68 kD).

Biochem/physiol Actions

Tau (τ) plays an essential role in the assembly and maintenance of microtubule structure. Deletion of tau (τ) results in developmental delay and learning disability. The gene expression is associated with the development of Alzheimer′s disease (AD). Genetic variation in τ gene increases the risk of susceptibility to the sporadic tauopathies, progressive supranuclear palsy (PSP) and corticobasal degeneration.

ANTI-PHOSPHO-TAU (PSER199/202) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-PHOSPHO-TAU (PSER199/202) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80

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• Anti-phospho-Tau (pSer199/202) antibody produced in rabbit
• ANTI-PHOSPHO-TAU (PSER199/202)
• Alphabetical Index
• Antibodies for Alzheimer and Neurodegenerative Disease ResearchCell Biology
• Antibodies for Neurobiology
• Antibodies for Neurodegenerative Diseases Research
• Antibodies to Cytoskeleton
• Antibodies to Microtubule and Associated ProteinsAntibodies