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Tabimorelin

Tabimorelin Struktur
193079-69-5
CAS-Nr.
193079-69-5
Englisch Name:
Tabimorelin
Synonyma:
NNC260703;NNC-260703;NNC26-0703;NNC-26-0703;Tabimorelin;Unii-L51cbe03kf;Tabimorelin [inn];N-[5-Amino-5-Methyl-2(E)-Hexenoyl]-N-Methyl-3-(2- Naphthyl)-D-Alanyl-N-Methyl-D-Phenylalanine Methylamide;D-Phenylalaninamide, N-[(2E)-5-amino-5-methyl-1-oxo-2-hexen-1-yl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-;N-[(2E)-5-Amino-5-methyl-1-oxo-2-hexenyl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamidehemifumarate
CBNumber:
CB31074328
Summenformel:
C32H40N4O3
Molgewicht:
528.68
MOL-Datei:
193079-69-5.mol

Tabimorelin Eigenschaften

Schmelzpunkt:
>70°C(dec.)
Siedepunkt:
794.4±60.0 °C(Predicted)
Dichte
1.146±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at RT
L?slichkeit
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
15.14±0.46(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilit?t:
Light Sensitive

Sicherheit

Tabimorelin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4.

Biologische Aktivit?t

Potent, orally active ghrelin receptor (GHS-R1a) agonist (K i = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC 50 value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats.

Tabimorelin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tabimorelin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 20)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037
3bsc@sina.com China 15838 69
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Beijing HuaMeiHuLiBiological Chemical 010-56205725
waley188@sohu.com China 12335 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Jiangsu Hongmin Pharmaceutical Co., Ltd. 18221292452
fannieliu@glschina.com China 6798 58
LGC Science (Shanghai) Ltd. 17717235263
fan.yang@LGCgroup.com China 18798 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016; 18162595016
3287908757@qq.com China 9119 58
Biosynth Biological Technology (Suzhou) Co Ltd --
sales@biosynth.com China 6051 58

  • Tabimorelin
  • Tabimorelin [inn]
  • Unii-L51cbe03kf
  • N-[(2E)-5-Amino-5-methyl-1-oxo-2-hexenyl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamidehemifumarate
  • N-[5-Amino-5-Methyl-2(E)-Hexenoyl]-N-Methyl-3-(2- Naphthyl)-D-Alanyl-N-Methyl-D-Phenylalanine Methylamide
  • NNC260703
  • NNC-260703
  • NNC-26-0703
  • NNC26-0703
  • D-Phenylalaninamide, N-[(2E)-5-amino-5-methyl-1-oxo-2-hexen-1-yl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-
  • 193079-69-5
  • C32H40N4O3189C4H4O4
  • C32H40N4O3
  • Amines
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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