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Gadobutrol

Gadobutrol Struktur
138071-82-6
CAS-Nr.
138071-82-6
Englisch Name:
Gadobutrol
Synonyma:
Gadavist;CL124;CS-113;gudobutrol;Gadobutrol;Gsdobutrol;Ggadobutrol;Gadobutrol Monomer;gadolinium butanol;Gadolinium cloth alcohol
CBNumber:
CB31118291
Summenformel:
C18H31N4O9.Gd
Molgewicht:
604.712
MOL-Datei:
138071-82-6.mol

Gadobutrol Eigenschaften

Schmelzpunkt:
>264°C (dec.)
Dichte
1.3 g/mL at 37 °C
storage temp. 
Refrigerator
L?slichkeit
Water (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
PH
6.6-8
InChIKey
ZPDFIIGFYAHNSK-IWEVFNEWNA-K
SMILES
N1(CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)[C@H](CO)[C@H](O)CO.[Gd+3] |&1:24,27,r|

Sicherheit

Toxizit?t LD50 i.v. in mice: 23 mmol/kg (Vogler)

Gadobutrol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Gadobutrol is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). It has a macrocyclic framework and is neutral. It is a water-soluble, highly hydrophilic compound with a partition coefficient between n-butanol and buffer at pH 7.6 of ~ 0.006.

Trademarks

Gadobutrol is marketed by Bayer AG as Gadovist, and by Bayer HealthCare Pharmaceuticals as Gadavist. In India, it is also marketed by Vivere Imaging as Viv-butrol.

Nebenwirkungen

Side effects of Gadobutrol are uncommon but may include: headache, nausea, vomiting, feeling unwell (malaise), dizziness, abnormal or unpleasant taste in your mouth, feeling hot, numbness or tingly feeling, itching or rash, skin redness, or injection site reactions (cold feeling, warmth, pain, or burning). Its more serious side effects include: urinating less than usual or not at all; drowsiness, confusion, mood changes, increased thirst, loss of appetite; swelling, weight gain, shortness of breath; seizures (convulsions); breathing problems; pounding heartbeats or fluttering in your chest; or severe pain, burning, or irritation around the IV needle.

Waste disposal

Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

Gadobutrol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Gadobutrol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 222)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
AFINE CHEMICALS LIMITED
+86-571-85134551
info@afinechem.com China 15081 58
HAINAN POLY PHARMCEUTICAL CO. LTD
+86-0571-89385087 +8613616530509
ff@hnpoly.com China 118 58
Xilinglab Co., Ltd.
+8618381337976
bd@xilinglab.com China 86 58
Guangzhou Tosun Pharmaceutical Ltd
+86-020-61855200-902 +8618124244216
info@upharm.cn China 897 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040
1056@dideu.com China 3971 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20122 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
+86-18600796368
sales@sjar-tech.com China 529 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21586 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58

138071-82-6()Verwandte Suche:


  • Gadobutrol
  • GadoliniuM,[10-[2,3-dihydroxy-1-(hydroxyMethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-
  • gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate
  • CL124
  • gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
  • CS-113
  • gudobutrol
  • Ggadobutrol
  • Gsdobutrol
  • Gadolinium cloth alcohol
  • Gadobutrol Monomer
  • gadolinium butanol
  • Lansoprazole Impurity 76
  • Gadavist
  • 138071-82-6
  • 62454-54-3
  • C18H31GdN4O9
  • C18H31GaN4O9
  • API
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