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DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Struktur
133156-06-6
CAS-Nr.
133156-06-6
Englisch Name:
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
Synonyma:
GR 73632;GR-73632 (GR73632);H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2;d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2;DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2;d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11);(DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11);δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
CBNumber:
CB3126730
Summenformel:
C40H59N7O6S
Molgewicht:
766
MOL-Datei:
133156-06-6.mol

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Eigenschaften

Siedepunkt:
1082.2±65.0 °C(Predicted)
Dichte
1.198±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Water:1.0(Max Conc. mg/mL);1.31(Max Conc. mM)
Aggregatzustand
Powder
pka
13.34±0.46(Predicted)
Farbe
White to off-white
Wasserl?slichkeit
Soluble to 1 mg/ml in water
InChIKey
HQKPTSSZOJLFBZ-LJADHVKFSA-N
SMILES
CSCC[C@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H]1CCCN1C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc3ccccc3)NC(=O)CCCCN)C(N)=O

Sicherheit

S-S?tze: 22-24/25
WGK Germany  3
Speicherklasse 11 - Combustible Solids

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

GR 73632 is a NK1 tachykinin receptor agonist used in the treatment of asthma and gastrointestinal disorders. It is involved in the contraction of muscles.

Allgemeine Beschreibung

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK1 is GR 64349 petpide.

Biochem/physiol Actions

GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 59)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30224 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634
Cecilia@youngshechem.com China 2345 58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.
+8615051830413
sales.njleonbiotech@gmail.com China 5482 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131956 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037
3bsc@sina.com China 15838 69
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853
ivy@hnhbsj.com China 7237 62
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659
sales@njleonbiotech.com China 5501 55

  • δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
  • N-(5-Amino-1-oxopentyl)-L-Phe-L-Phe-L-Pro-N-methyl-L-Leu-L-Met-NH2
  • (2S)-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]-N-methyl-pyrrolidine-2-carboxamide
  • (2S)-N-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenylpropanoyl]amino]-3-phenylpropanoyl]-N-methylpyrrolidine-2-carboxamide
  • (2S)-N-[(2S)-1-[[(2S)-1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl]amino]-4-methyl-1-oxo-pentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-azanylpentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-methyl-pyrrolidine-2-carboxamide
  • d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
  • d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2
  • GR 73632
  • H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2
  • (DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11)
  • DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
  • DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11)
  • L-Methioninamide,N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanyl-L-prolyl-N-methyl-L-leucyl-
  • GR-73632 (GR73632)
  • δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
  • Neurokinin Receptor,NK receptor,Tachykinin receptor,GR73632,inhibit,Inhibitor,GR-73632,GR 73632
  • 133156-06-6
  • C40H59N7O6S
  • Peptides
  • Tachykinins
  • Biochemicals and Reagents
  • Agonist
  • Amino Acids and Peptides
  • BioChemical
  • AgonistPeptides for Cell Biology
  • Neuropeptides
  • Peptides for Cell Biology
  • Tachykinins
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