pyridoxal isonicotinoyl hydrazone
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- CAS-Nr.
- 737-86-0
- Englisch Name:
- pyridoxal isonicotinoyl hydrazone
- Synonyma:
- NSC 77674;PIH - CAS 737-86-0 - Calbiochem;Pyridoxal isonicotinoyl hydrazine;PIH(Pyridoxal isonicotinoyl hydrazine);Pyridoxal isonicotinoyl hydrazone (PIH);PIH - CAS 737-86-0 - Calbiochem[528110];PIH - CAS 737-86-0 - Calbiochem[528110-50MG];inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor;Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide
- CBNumber:
- CB31370372
- Summenformel:
- C14H14N4O3
- Molgewicht:
- 286.29
- MOL-Datei:
- 737-86-0.mol
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pyridoxal isonicotinoyl hydrazone Eigenschaften
- Schmelzpunkt:
- 261-262 °C (decomp)
- Dichte
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- +2C to +8C
- L?slichkeit
- DMF: 1 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.5 mg/ml
- Aggregatzustand
- Yellow solid
- pka
- 8.04±0.10(Predicted)
- Farbe
- yellow
- InChI
- 1S/C14H14N4O3/c1-9-13(20)12(11(8-19)6-16-9)7-17-18-14(21)10-2-4-15-5-3-10/h2-7,17,19H,8H2,1H3,(H,18,21)/b12-7+
- InChIKey
- HOYFGBFEIXEDEL-KPKJPENVSA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 1 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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pyridoxal isonicotinoyl hydrazone Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Pyridoxal Isonicotinoyl Hydrazone is a cell-permeable non-toxic iron chelator of the aroyl hydrazone class.
Allgemeine Beschreibung
A cell-permeable, non-toxic tridendate iron (Fe
3+) chelator of the aroyl hydrazone class. Even at low concentrations, highly effective in mobilizing Fe
3+ from cells and preventing its uptake from transferrin, even at low concentrations. Exhibits similar specificity and binding affinity as Deferoxamine Mesylate (Cat. No.
252750) but has greater access to mitochondrial iron. Also useful for the management of iron overload disease in experimental models. Inhibits the induction of heme containing indoleamine 2,3-dioxygenase activity.
pyridoxal isonicotinoyl hydrazone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
pyridoxal isonicotinoyl hydrazone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 58)Lieferanten
- Pyridoxal isonicotinoyl hydrazone (PIH)
- NSC 77674
- PIH(Pyridoxal isonicotinoyl hydrazine)
- PIH - CAS 737-86-0 - Calbiochem
- Pyridoxal isonicotinoyl hydrazine
- 4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide
- N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide
- inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor
- Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator
- PIH - CAS 737-86-0 - Calbiochem[528110]
- PIH - CAS 737-86-0 - Calbiochem[528110-50MG]
- 737-86-0
