1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid
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- CAS-Nr.
- 129-74-8
- Bezeichnung:
- 1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid
- Englisch Name:
- BUCLIZINE, DIHYDROCHLORIDE
- Synonyma:
- POSDEL;BUCLINA;softran;aphilanr;buclodin;UCB-4445;VIBAZINE;LONGIFENE;BUCLIZINE 2HCL;1-(4-(tert-Butyl)
- CBNumber:
- CB3156784
- Summenformel:
- C28H35Cl3N2
- Molgewicht:
- 505.95
- MOL-Datei:
- 129-74-8.mol
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1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid Eigenschaften
- Schmelzpunkt:
- 230-240°C
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilit?t:
- Hygroscopic
- InChI
- 1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H
- InChIKey
- SDBHDSZKNVDKNU-UHFFFAOYSA-N
- SMILES
- [Cl-].[Cl-].Clc1ccc(cc1)C(N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C)c2ccccc2.[H+].[H+]
- CAS Datenbank
- 129-74-8
- EPA chemische Informationen
- Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride (129-74-8)
Sicherheit
| WGK Germany |
WGK 3 |
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| TSCA |
TSCA listed |
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| Speicherklasse |
11 - Combustible Solids |
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1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
BUCLIZINE, DIHYDROCHLORIDE is Off-White Powder
Verwenden
BUCLIZINE, DIHYDROCHLORIDE used as an antiemetic
Allgemeine Beschreibung
Buclizine hydrochloride, l-(p-tertbutylbenzyl)-4-(p-chloro-α-phenylbenzyl)piperazinedihydrochloride (Bucladin-S), is a white to slightly yellowcrystalline powder that is insoluble in water. The highlylipid-soluble buclizine has CNS depressant, antiemetic, andantihistaminic properties. This drug has been discontinued inthe United States.
Sicherheitsprofil
Poison by
intraperitoneal route. An experimental
teratogen. When heated to decomposition it
emits very toxic fumes of NOx, and HCl.
1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 153)Lieferanten
129-74-8(1-((4-Chlorphenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)-methyl)piperazin-dihydrochlorid)Verwandte Suche:
- 1-(p-tert-butylbenzyl)-4-(p-chloro-alpha-phenylbenzyl)-piperazindihydrochl
- 1-(p-tert-butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazinedihydrochloride
- 1-(p-tert-butylbenzyl-4-p-chloro-alpha-phenylbenzyl)piperazinedihydrochlorid
- 1-p-chlorobenzhydryl-4-p-(t)-butylbenzylpiperazinedihydrochloride
- aphilanr
- buclizinehydrochloride
- buclodin
- LONGIFENE
- 1-(p-chlorobenzhydryl)-4-(p-t-butylbenzyl)diethylenediaminedihydrochloride
- BUCLINA
- BUCLIZINE, DIHYDROCHLORIDE
- 1-(4-(tert-Butyl)
- -4-((4-chlorophenyl)
- UCB-4445
- VIBAZINE
- POSDEL
- BUCLIZINE 2HCL
- Histabutizine dihydrochloride
- UCB-4445, Buclina, Longifene, Posdel, Vibazine
- piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]me
- softran
- 1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(tert-butyl)phenyl]methyl]piperazine dihydrochloride
- 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)Methyl)piperazine dihydrochloride
- Buclizine Hydrochloride(BP/EP)
- Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2)
- histabutyzinedihydrochloride
- 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)meth
- Buclizine USP/EP/BP
- BUCLIZINE, DIHYDROCHLORIDE USP/EP/BP
- Chlorphenazine hydrochloride
- Buclizine HCl (UCB-4445)
- Buclizine D8 DihydrochlorideQ: What is
Buclizine D8 Dihydrochloride Q: What is the CAS Number of
Buclizine D8 Dihydrochloride Q: What is the storage condition of
Buclizine D8 Dihydrochloride
- teratogen,Inhibitor,MCF-7,anti-tumor activity,antiallergic,antihistamine,inhibit,Histamine Receptor,Buclizine,Buclizine dihydrochloride
- 1-(4-(tert-butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine hydrochloride
- Buclizine dihydrochloride, 10 mM in DMSO
- 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)(phenyl)methyl]piperazine dihydrochloride
- 129-74-8
- C28H35Cl3N2
- C28H33ClN22HCl
- C28H37Cl3N2
- C28H33ClN22ClH
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Inhibitors
