tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
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- CAS-Nr.
- 167081-37-0
- Englisch Name:
- tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
- Synonyma:
- trans-1-(Boc-aMino)-3-(hy...;tert-Butyl (trans-3-(hydroxymethyl);trans-3-(Boc-amino)cyclobutanemethanol;trans-3-(Boc-amino)cyclobutanemethanol,97%;trans-3-(Boc-aMino)cyclobutaneMethanol, 97%;BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE;trans-1-(Boc-aMino)-3-(hydroxyMethyl)cyclobutane;tert-butyl N-[3-(hydroxymethyl)cyclobutyl]carbamat;TERT-BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE;tert-butyl (1r,3r)-3-(hydroxymethyl)cyclobutylcarbamate
- CBNumber:
- CB3158733
- Summenformel:
- C10H19NO3
- Molgewicht:
- 201.26
- MOL-Datei:
- 167081-37-0.mol
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tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Eigenschaften
- Siedepunkt:
- 317.9±11.0 °C(Predicted)
- Dichte
- 1.08±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C, stored under nitrogen
- pka
- 12.42±0.40(Predicted)
- Aussehen
- White to off-white Solid
- InChI
- InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-8-4-7(5-8)6-12/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8-
- InChIKey
- PCPNTJQMXAHNOA-ZKCHVHJHSA-N
- SMILES
- C(OC(C)(C)C)(=O)N[C@@H]1C[C@@H](CO)C1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
To a stirred solution of methyl (1R,3R)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate (1.0 g, 4.4 mmol) in THF (20 mL) was added 3M lithium borohydride (9 mL, 9 mmol) at 0° C. Then the reaction mixture was heated and stirred at 60° C for 3 h. The reaction mixture was then transferred into dilute NaOH and the resulting mixture was extracted using ethyl acetate (3×50 mL). The combined organic layer was dried over anhydrous sodium sulfate and filtered. The filtrate was evaporated under reduced pressure and the crude product was purified using silica gel column chromatography (3% MeOH-DCM) to give tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate as a white solid (0.8 g, 91%).
tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 62)Lieferanten
167081-37-0()Verwandte Suche:
- trans-1-(Boc-aMino)-3-(hy...
- trans-1-(Boc-aMino)-3-(hydroxyMethyl)cyclobutane
- trans-3-(Boc-aMino)cyclobutaneMethanol, 97%
- BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE
- tert-Butyl (trans-3-(hydroxymethyl)
- TERT-BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE
- tert-butyl N-[trans-3-(hydroxymethyl)cyclobutyl]carbamate
- Carbamic acid, [3-(hydroxymethyl)cyclobutyl]-, 1,1-dimethylethyl ester, trans-
- trans-1-(Boc-amino)-3-(hydroxymethyl)cyclobutane - SB7652
- tert-butyl (1r,3r)-3-(hydroxymethyl)cyclobutylcarbamate
- Carbamic acid, N-[trans-3-(hydroxymethyl)cyclobutyl]-, 1,1-dimethylethyl ester
- trans-3-(Boc-amino)cyclobutanemethanol,97%
- tert-butyl N-[3-(hydroxymethyl)cyclobutyl]carbamat
- trans-3-(Boc-amino)cyclobutanemethanol
- 1,1-Dimethylethyl N-[trans-3-(hydroxymethyl)cyclobutyl]carbamate
- 167081-37-0
- 167081-30-0
- N-BOC
