p53 human Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
p53 human has been used in dot blot.
Allgemeine Beschreibung
p53 protein is composed of an N-terminal domain with a transactivation domain and proline-rich region, a central core-DNA binding domain, and a C-terminal domain with tetramerization and regulatory domains. The TP53 gene which encodes for the p53 protein is mapped on the human chromosome at 17p13.1.
Biochem/physiol Actions
p53 protein acts as a transcription factor that participates in regulating positively or negatively the expression of several responsive genes. It plays a role in regulating angiogenesis, cellular senescence, autophagy, cell survival, differentiation, and oxidative stress. Mutations in the TP53 gene lead to Li Fraumeni cancer syndrome.
p53 human Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
