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Tianeptine

Tianeptine Struktur
66981-73-5
CAS-Nr.
66981-73-5
Englisch Name:
Tianeptine
Synonyma:
Tianeptine hemisulfate monohydrate;Tianeptine sulphate;Tianeptina;Tianeptineacid;Tianeptine powder;COAXIL;Tinepin;Tianepine;Tineptine;Tianeotine
CBNumber:
CB3217470
Summenformel:
C21H25ClN2O4S
Molgewicht:
436.95
MOL-Datei:
66981-73-5.mol

Tianeptine Eigenschaften

Schmelzpunkt:
129-131°C
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
Freely soluble in water, in methanol and in methylene chloride.
Aggregatzustand
Solid
Farbe
White to Off-White
InChIKey
JICJBGPOMZQUBB-UHFFFAOYSA-N
SMILES
C(O)(=O)CCCCCCNC1C2=CC=C(Cl)C=C2S(=O)(=O)N(C)C2=CC=CC=C21
CAS Datenbank
66981-73-5(CAS DataBase Reference)

Sicherheit

RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III

Tianeptine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake.

Chemische Eigenschaften

White Solid

Verwenden

Tianeptine is used in the treatment of reactive and neurotic depression, as well as in the treatment of anxious states.

Verwenden

Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant

Biologische Aktivit?t

Tianeptine was identified as an efficacious MOR full agonist, binding to the human MOR with a Ki of 383 ± 183 nM. Tianeptine was also found to act as a full agonist at the DOR, although it had much lower potency and was inactive at the KOR. The MOR was required for the acute and chronic antidepressant-like effects of tianeptine in mice. Although tianeptine also produced behavioural effects, including analgesia and reward, its effects were distinct from morphine in that it did not produce tolerance or withdrawal.

Nebenwirkungen

Taking high doses of tianeptine can cause drowsiness, confusion, difficulty breathing, coma, and death. Long-term use can cause dependence and withdrawal.

Tianeptine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tianeptine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 310)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou multinpharma Co.,Ltd
+86-13655719091 +86-13655719091
renecltd@aliyun.com China 135 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533
Brad@rongnabiotech.com China 3364 58
Forest chemical technology
+86-13854236000; +8613854236000
grant@forestchem.freeqiye.com China 296 58
Shanghai Longyu Biotechnology Co., Ltd.

info@longyupharma.com China 2421 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605
info@millionpharm.com China 185 58
LIDE PHARMACEUTICALS LIMITED
+86-86-2558409506 +8618913920737
louis@lidepharma.com China 300 58
Hebei Dangtong Import and export Co LTD
+86-86-4001020630 +8619831957301
admin@hbdangtong.com China 1000 58
Hangzhou Beiputai Biomedical
+852-54232901;0571-85350119 +852-54232901
guidrywang@outlook.com China 22 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+8617392709771
1097@dideu.com China 3993 58

66981-73-5()Verwandte Suche:


  • 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)-amino]heptanoic acid s,s-dioxide
  • 7-[(3-CHLORO-6,11-DIHYDRO-6-METHYL-DIBENZO[C,F][1,2]THIAZEPINE-11-YL)AMINO]HEPTANOIC ACID S,S DIOXIDE
  • COAXIL
  • 7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-y1)amino]heptanoic acid S,S-dioxide
  • Brn 1232295
  • Heptanoic acid, 7-((3-chloro-6,11-dihydro-6-methyldibenzo(E,F)(1,2)thiazapin-11-yl)amino)-, S,S-dioxide
  • Tianeptina [inn-spanish]
  • Tianeptinum
  • Tianeptine-d4
  • Tianeotine
  • Heptanoic acid,7-[(3-chloro-6,11-dihydro-6-Methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)aMino]-
  • Tianeptine 7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)-amino]heptanoic acid S,S-dioxide
  • 7-[(3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl)amino]heptanoic acid
  • Thiempirtine
  • Sodium Tianeptine for system suitability CRS
  • Raw Material Tianeptine Acid
  • Tianeptine crystal
  • Tianeptine(INN)
  • Tianeptine USP/EP/BP
  • tianeptine sodium tianeptine sulfate Tianeptine acid
  • Tianeptineacid
  • Tianeptine hemisulfate monohydrate
  • Tianeptine powder
  • Tianepine
  • Tianeptine,Tianeptine Ethyl Ester
  • α-Iodo-4-methylpropiophenone
  • Thioneptine
  • Tinepin
  • Tianeptine in Methanol
  • Tineptine
  • Tinapentin acid
  • Tianeptine (Acid Form)
  • Tianeptine sulphate
  • Tianeptina
  • Tianeptine sour
  • 66981-73-5
  • C21H25ClN2O4S
  • Tianeptine
  • API
  • Tianeptine Intermediates
  • Pharmaceuticals
  • Heterocyclic Compounds
  • Intermediates & Fine Chemicals
  • Intermediate
  • 66981-73-5
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