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TRIMIDOX

TRIMIDOX Struktur
95933-74-7
CAS-Nr.
95933-74-7
Englisch Name:
TRIMIDOX
Synonyma:
VF 233;TRIMIDOX;Trimidox Exclusive;MSLJYSGFUMYUDX-UHFFFAOYSA-N;N,3,4,5-TETRAHYDROXY-BENZENECARBOXIMIDAMIDE;Benzenecarboximidamide, N,3,4,5-tetrahydroxy-;4-[amino-(hydroxyamino)methylidene]-2,6-dihydroxycyclohexa-2,5-dien-1-one
CBNumber:
CB32446894
Summenformel:
C7H8N2O4
Molgewicht:
184.15
MOL-Datei:
95933-74-7.mol

TRIMIDOX Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid

Sicherheit

TRIMIDOX Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in HL-60 cells, inducing apoptosis via activation of caspases without altering the cell cycle distribution. Trimidox inhibits growth of human promyelocytic leukemia HL-60 cells with an IC50 value of 35 μM.

Verwenden

Trimidox is a specific ribonucleotide reductase inhibitor.

TRIMIDOX Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


TRIMIDOX Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 23)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8140 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11972 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041
2851167782@qq.com China 10935 58
Cayman Chemical Company --
sales@caymanchem.com China 6838 58
Santa Cruz Biotechnology Inc --
scbt@scbt.com China 6594 58
ApexBio Technology --
sales@apexbt.com United States 6251 58
Guangzhou Squirrel Biotechnology Co., Ltd. --
CHINA 6609 58
Shanghai Hongyu Biotechnology Co., Ltd. --
CHINA 547 58

  • TRIMIDOX
  • VF 233
  • Trimidox Exclusive
  • MSLJYSGFUMYUDX-UHFFFAOYSA-N
  • 4-[amino-(hydroxyamino)methylidene]-2,6-dihydroxycyclohexa-2,5-dien-1-one
  • Benzenecarboximidamide, N,3,4,5-tetrahydroxy-
  • N,3,4,5-TETRAHYDROXY-BENZENECARBOXIMIDAMIDE
  • 95933-74-7
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