ANTI-MUNC-18-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Munc-18-1 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

Allgemeine Beschreibung

Munc-18-1 (67 kDa) is an abundant neuronal protein that tightly binds to the synaptic fusion protein syntaxin. It is primarily expressed in neuronal tissues. Both Munc-18-1 and 2 isoforms bind tightly to syntaxins 1A, 2, and 3.

Biochem/physiol Actions

Munc-18-1 functions in synaptic vesicle exocytosis. It modulates neurotransmission by associating with syntaxin 1. Munc-18-1 binds to both syntaxin 1A and 1B isoforms, inhibiting the binding of t-soluble N-ethylmaleimide-sensitive factor-attached protein receptor (SNARE) synaptobrevin/vesicle-associated membrane protein (VAMP) and SNAP25 to syntaxin 1 and preventing SNARE assembly. Munc-18 is required for neurotransmitter secretion from synaptic vesicles throughout development and has been implicated in axonal branching in hippocampal neurons.

ANTI-MUNC-18-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-MUNC-18-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Atlas antibodies	--	order@atlasantibodies.com	China	6586	58
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58
Guangzhou Yanna Biotechnology Co., Ltd.	--		CHINA	6572	58

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• Anti-Munc-18-1 antibody produced in rabbit
• Monoclonal Anti-STXBP1 antibody produced in mouse
• Anti-MUNC18/STXBP1 (Isoform A) antibody produced in goat
• ANTI-MUNC-18ALPHA
• ANTI-MUNC-18-1
• ANTI-RB-SEC-1
• ANTI-SYNTAXIN-BINDING PROTEIN 1
• ANTI-STXBP1
• Anti-Munc-18α, Anti-rb-Sec-1, Anti-STXBP1, Anti-Syntaxin-binding protein 1
• Anti-HUNC18
• Anti-UNC18