5-Azidopentanoic acid
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- CAS-Nr.
- 79583-98-5
- Englisch Name:
- 5-Azidopentanoic acid
- Synonyma:
- 5-Azidovaleric acid;d-Azidovaleric acid;5-AZIDO-PENTANOIC ACID;CilostazolImpurity7-d8;5-AZIDO-VALERIANIC ACID;5-Azidovaleric Acid >5-Azidopentanoic acid, ≥97%;5-Azidopentanoic acid - A1942;5-Azidopentanoic acid >=97.0%
- CBNumber:
- CB32466229
- Summenformel:
- C5H9N3O2
- Molgewicht:
- 143.145
- MOL-Datei:
- 79583-98-5.mol
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5-Azidopentanoic acid Eigenschaften
- Siedepunkt:
- 85°C/0.01mmHg(lit.)
- Dichte
- 1.142
- Brechungsindex
- 1.4640-1.4680
- storage temp.
- -20°C
- L?slichkeit
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- Aggregatzustand
- clear liquid
- Farbe
- Colorless to Red to Green
- BRN
- 1706398
- InChI
- InChI=1S/C5H9N3O2/c6-8-7-4-2-1-3-5(9)10/h1-4H2,(H,9,10)
- InChIKey
- SBZDIRMBQJDCLB-UHFFFAOYSA-N
- SMILES
- C(C(O)=O)CCCN=[N+]=[N-]
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
40 |
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| S-S?tze: |
36/37 |
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| WGK Germany |
3 |
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| HS Code |
29299090 |
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| Speicherklasse |
5.2 - Organic peroxides and self-reacting hazardous materials |
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| Hazard Classifications |
Carc. 1B
Self-react. C |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H242 |
Erw?rmung kann Brand verursachen. |
Organische Peroxide |
Typen C & D |
Achtung
Warnung |
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P210, P220, P234, P280, P370+P378,P403+P235, P411, P420, P501 |
| H350 |
Kann Krebs verursachen. |
Karzinogenit?t |
Kategorie 1A |
Achtung |
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| Sicherheit |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P235 |
Kühl halten |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P370+P378 |
Bei Brand: zum L?schen verwenden. |
| P403 |
An einem gut belüfteten Ort aufbewahren. |
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5-Azidopentanoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Yellow liquid
Verwenden
5-Azidopentanoic acid can be used to synthesize:
- Chitosan-poly(ethylene glycol) hydrogels by azide–alkyne click chemistry.
- 5-iodo-1,2,3-triazole containing macrocycles.
- Bivalent quinine dimers intervening triazole ring used as inhibitors of P-glycoprotein (P-gp) mediated cellular efflux.
Synthese
C7H13N302 C5H9N302 29.1 mmol Lithium hydroxide monohydrate as a 1 M solution in Water, 90 ml THF and 90 ml methanol was added to 15.4 mmol Ethyl-5-Azido pentanoate in a flask and stirred at room temperature for 18 hours. The solvent was removed in vacuo and a small amount of water and HCI 37 % was added till pH 1 . After that the reaction mixture was extracted with Ethyl acetate (250 ml) and the combined organic phase was dried over Na2SO4. The solvent was removed in vacuo leaving 2.18 g of 5-Azidopentanoic acid (15.2 mmol, yield = 99 %).
[1]
5-Azidopentanoic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Azidopentanoic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 112)Lieferanten
- 5-AZIDO-PENTANOIC ACID
- 5-AZIDO-VALERIANIC ACID
- d-Azidovaleric acid
- 5-Azidovaleric acid
- 5-Azidopentanoic acid >=97.0%
- 5-Azidopentanoic acid - A1942
- 5-Azidovaleric Acid >
- 5-Azidopentanoic acid, ≥97%
- CilostazolImpurity7-d8
- 79583-98-5
- 79593-98-5
- Click Chemistry Reagents
