2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
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- CAS-Nr.
- 97657-92-6
- Englisch Name:
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
- Synonyma:
- CS-784;DiMebone HCl;Dimebon 2HCl;Latrepirdine 2HCl;DiMebone dihydrochloride;Latrepirdine 2HCl ，S1245;DiMeboline dihydrochloride;Latrepirdine dihydrochloride;Latrepirdine (Dimebolin) HCl;Dimebone dihydrochloride hydrate
- CBNumber:
- CB32489958
- Summenformel:
- C21H25N3.2ClH
- Molgewicht:
- 392.371
- MOL-Datei:
- 97657-92-6.mol
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2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride Eigenschaften
- Schmelzpunkt:
- 220-222 °C
- storage temp.
- Desiccate at RT
- L?slichkeit
- H2O: ≥10mg/mL
- Aggregatzustand
- powder
- Farbe
- white to off-white
- Wasserl?slichkeit
- H2O: ≥10mg/mL
- InChI
- 1S/C21H25N3.2ClH.H2O/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;;;/h4-7,12-13H,8-11,14H2,1-3H3;2*1H;1H2
- InChIKey
- QQHQMWVYYVVAOV-UHFFFAOYSA-N
- SMILES
- O.Cl.Cl.CN1CCc2c(C1)c3cc(C)ccc3n2CCc4ccc(C)nc4
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22-36/38 |
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| S-S?tze: |
26-36/39 |
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| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Latrepirdine is an antihistamine drug used initially in Russia. Recently research have explore the potential of Latrepirdine to demonstrate activities against neurodegenerative conditions.
Biologische Aktivit?t
Non-selective antihistamine that displays cognitive enhancing abilities. Also displays high affinity for 5-HT (particularly 5-HT 6 and 5-HT 7 ), α -adrenergic, dopaminergic, AMPA and NMDA receptors, and L-type calcium channels. Exhibits neuroprotective activity in cellular models of Alzheimer's and Huntington's disease and preserves cognitive function following administration to AF64A lesioned rats. Protects neurons against the neurotoxic action of β -amyloid fragment.
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 125)Lieferanten
97657-92-6()Verwandte Suche:
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
- Dimebon 2HCl
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indoledihydrochloride
- DiMebone HCl
- DiMeboline dihydrochloride
- DiMebone dihydrochloride
- Latrepirdine dihydrochloride
- 2,8-dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride
- 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate
- Dimebolin dihydrochloride hydrate
- Dimeboline dihydrochloride hydrate
- Dimebone dihydrochloride hydrate
- CS-784
- Latrepirdine 2HCl
- 2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole hydrochloride
- 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole,dihydrochloride
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride ISO 9001：2015 REACH
- Latrepirdine (Dimebolin) HCl
- Dimebolin dihydrochloride|||Latrepirdine|||Latrepirdine 2HCl|||Dimebolin
- Latrepirdine dihydrochloride, 10 mM in DMSO
- 2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride , Latrepirdine 2HCl
- 2,3,4,5-Tetrahydro-2,8-dimethy1-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
- Latrepirdine 2HCl ，S1245
- 97657-92-6
- C21H25N32HCl
- C21H25N32ClH
- C21H27Cl2N3
- Inhibitors
