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Brinzolamide-d5

Brinzolamide-d5 Struktur
1217651-02-9
CAS-Nr.
1217651-02-9
Englisch Name:
Brinzolamide-d5
Synonyma:
Brinzolamide-d5;[2H5]-Brinzolamide;(R)-4-((ethyl-d5)amino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
CBNumber:
CB32507883
Summenformel:
C12H21N3O5S3
Molgewicht:
383.5
MOL-Datei:
1217651-02-9.mol

Brinzolamide-d5 Eigenschaften

storage temp. 
Refrigerator
L?slichkeit
Ethanol
Aggregatzustand
Solid
Farbe
Crystalline

Sicherheit

Brinzolamide-d5 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Brinzolamide-d5 is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.

Chemische Eigenschaften

Crystalline Solid

Verwenden

Carbonic anhydrase inhibitor. Antiglaucoma agent.

Brinzolamide-d5 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Brinzolamide-d5 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 29)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9804 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761
3003392093@yongstandards.com China 9942 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 45000 58
CHINA ISOTOPE CO., LIMITED 02151600108 13062666369
info@isotopechem.com China 4724 58
Shanghai Beiwanta Biotechnology Co., Ltd. 021-67187366 19901745723
info@bwtlab.com China 9796 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900
judy.xia@synzest.com China 12582 58
BePure (Beijing) Biotechnology Co. --
7993601name@qq.com CHINA 6620 58

1217651-02-9()Verwandte Suche:


  • [2H5]-Brinzolamide
  • Brinzolamide-d5
  • (R)-4-((ethyl-d5)amino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
  • 1217651-02-9
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
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