(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
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- CAS-Nr.
- 80751-65-1
- Englisch Name:
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- Synonyma:
- Cl-apb;Chloro-AP;SK&F 82958;SKF82958 HBr;SKF82958,SKF 82958;6H-Benzo[cd]pyren-7-one;(±)-SKF 82958;CHLORO-APB;(+/-)-SKF-82958 HYDROBROMIDE;(+/-)-Chloro-apbhydrobromide;(+/-)-CHLORO-APB HYDROBROMIDE
- CBNumber:
- CB3251102
- Summenformel:
- C19H20ClNO2
- Molgewicht:
- 329.82
- MOL-Datei:
- 80751-65-1.mol
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Eigenschaften
- Siedepunkt:
- 473.7±45.0 °C(Predicted)
- Dichte
- 1.234±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 3.7 mg/mL
- Aggregatzustand
- solid
- pka
- 8.73±0.40(Predicted)
- Farbe
- tan
- Wasserl?slichkeit
- H2O: 3.7mg/mL
aqueous base: unstable
ethanol: soluble
- InChI
- 1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H
- InChIKey
- WLXGFAVTAAQOFH-UHFFFAOYSA-N
- SMILES
- Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3
Sicherheit
| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.
Biochem/physiol Actions
Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 39)Lieferanten
80751-65-1()Verwandte Suche:
- (+/-)-SKF-82958 HYDROBROMIDE
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- 6-CHLORO-N-ALLYL-SKF-38393 HYDROBROMIDE
- SK&F 82958
- (±)-SKF-82958 hydrobromide, 6-Chloro-N-allyl-SKF-38393 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol
- 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-
- 6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
- Cl-apb
- SKF82958 HBr
- 3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
- (+/-)-CHLORO-APB HYDROBROMIDE
- (+/-)-CHLORO-APB HYDROBROMIDE ((+/-)-SKF -82958 HBR)
- (±)-SKF 82958;CHLORO-APB
- 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
- (+/-)-Chloro-apbhydrobromide
- Chloro-AP
- 6H-Benzo[cd]pyren-7-one
- SKF82958,SKF 82958
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-P...
- 80751-65-1
- C19H20ClNO2HBr
