(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

JNJ-5207787 is an antagonist of the neuropeptide Y (NPY) receptor Y₂ that blocks peptide YY binding (IC₅₀ = 100 nM). It displays 100-fold selectivity for Y₂ over other NPY receptors and has minimal effect on a panel of 50 receptors, ion channels, and transporters, except for sodium channel 2. JNJ-5207787 is intraperitoneally bioavailable and brain penetrant in rats, occupying maximally 50% of Y₂ receptor binding sites in the hypothalamic area.

Verwenden

JNJ 5207787 is a small molecule antagonist of the neuropeptide Y Y2 receptor.

(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai YuanYe Biotechnology Co., Ltd.	13636370518	shyysw007@163.com	China	89686	60
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28768	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	4334	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	024-88590548 18698872706	757984502@qq.com	China	962	58
Wuhan Jingkangen Biomedical Technology Co., Ltd	13720134139 086-15871494362 13720134139	orders@jknbiochem.com	China	7231	58

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• (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide
• JNJ 5207787
• trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]acrylamide
• (E)-N-(1-acetyl-2,3-dihydroindol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]prop-2-enamide
• 2-Propenamide, N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-, (2E)-
• 683746-68-1
• C32H38N4O2