Glutaminase C-IN-1

311795-38-7

CAS-Nr.: 311795-38-7

Englisch Name:: Glutaminase C-IN-1

Synonyma:: Compound 968;CS-2083;GLS-IN-968;GAC Inhibitor 968;Glutaminase C-IN-1;Glutaminase C-IN-1 (968);Glutaminase C inhibitor 1;glutaminase inhibitor 968;Glutaminase C-IN-1 ，E2365;Glutaminase C-IN-1, 10 mM in DMSO

CBNumber:: CB32561506

Summenformel:: C27H27BrN2O

Molgewicht:: 475.42

MOL-Datei:: 311795-38-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 72

Glutaminase C-IN-1 Eigenschaften

Siedepunkt:: 623.2±55.0 °C(Predicted)

Dichte: 1.39±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

L?slichkeit: Soluble in DMSO (up to 11 mg/ml) or in Ethanol (up to 1 mg/ml with warming)

pka: 4.09±0.42(Predicted)

Aggregatzustand: powder

Farbe: white to beige

Stabilit?t:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

InChI: 1S/C27H27BrN2O/c1-27(2)14-19-24-18-8-6-5-7-16(18)9-11-21(24)29-26(25(19)23(31)15-27)17-10-12-22(30(3)4)20(28)13-17/h5-13,26,29H,14-15H2,1-4H3

InChIKey: NVFRRJQWRZFDLM-UHFFFAOYSA-N

SMILES: Brc1c(ccc(c1)C2Nc3c(c5c(cc3)cccc5)C4=C2C(=O)CC(C4)(C)C)N(C)C

Sicherheit

WGK Germany	WGK 3
Speicherklasse	11 - Combustible Solids

Glutaminase C-IN-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Glutaminase inhibitor 968 has been used to study the role of glutamine metabolism in macrophage activation.

Allgemeine Beschreibung

Glutaminase Inhibitor 968 belongs to the benzophenanthridinone family.

Biochem/physiol Actions

Glutaminase Inhibitor 968 is an allosteric inihibitor of the mitochondrial enzyme glutaminase C (GAC), which is overexpressed in a number of cancer cell lines. Glutaminase Inhibitor 968 shows 21% inhibition at 10 μM, 94% at 25 μM. Glutaminase Inhibitor 968 blocked human cancer cell proliferation in culture, and in inhibited tumor formation in mouse xenograft models.

Glutaminase C-IN-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Glutaminase C-IN-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 72)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39039	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11680	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9416	55
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16101	64

5-[3-BroMo-4-(diMethylaMino)phenyl]-2,3,5,6-tetrahydro-2,2-diMethylbenzo[a]phenanthridin-4(1H)-one
Glutaminase C-IN-1
Glutaminase C-IN-1 (968)
Glutaminase Inhibitor Compound 968
glutaminase inhibitor 968
CS-2083
5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one
Glutaminase C inhibitor 1
Benzo[a]phenanthridin-4(1H)-one, 5-[3-bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethyl-
Glutaminase Inhibitor 968 >=98% (HPLC)
GLS-IN-968
GAC Inhibitor 968
Compound968,Glutaminase,Glutaminase CIN1,Glutaminase C IN 1,Compound-968,inhibit,Inhibitor
Glutaminase C-IN-1, 10 mM in DMSO
Glutaminase C inhibitor 968 (Compound 968)
Glutaminase C-IN-1 ，E2365
Compound 968
311795-38-7

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