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Virginiamycin M1

VIRGINIAMYCIN M1 Struktur
21411-53-0
CAS-Nr.
21411-53-0
Bezeichnung:
Virginiamycin M1
Englisch Name:
VIRGINIAMYCIN M1
Synonyma:
Pristinamycin IIA;Streptogramin A;C11299;PA 114A;Factor M;NSC 87432;NSC 244426;MIKAMYCIN A;Vernamycin A;STAPHYLOMYCIN
CBNumber:
CB3294594
Summenformel:
C28H35N3O7
Molgewicht:
525.59
MOL-Datei:
21411-53-0.mol

Virginiamycin M1 Eigenschaften

Schmelzpunkt:
165-167℃
alpha 
D20 -218° ( c = 0.34 in ethanol)
Siedepunkt:
825.2±65.0 °C(Predicted)
Dichte
1.26±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
chloroform/methanol: soluble10mg/mL
Aggregatzustand
powder
pka
13.18±0.70(Predicted)
Farbe
yellow to tan
Stabilit?t:
Light Sensitive
InChIKey
DAIKHDNSXMZDCU-QHKJSJJMSA-N
SMILES
CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C[C@H]1C)n3
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
HS Code  29419090
Speicherklasse 11 - Combustible Solids
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Virginiamycin M1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Light yellow powder

Verwenden

Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA.

Definition

ChEBI: A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms includ ng methicillin-resistant Staphylococcus aureus.

Kontakt-Allergie

Like the other streptogramin, pristinamycin, virginiamycin is made of two subunits, virginiamycin S1 and virginiamycin M1. Dermatitis was quite common in people using the formerly available topical virginiamycin. Occupational dermatitis was observed in the pharmaceutical industry, in breeders, and in a surgeon who used topical virginiamycin on postoperative wounds (personal observation).

Virginiamycin M1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Virginiamycin M1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 131)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19936 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29792 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750
info@finetechnology-ind.com China 9539 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39039 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618791163155
18791163155@163.com China 3397 58
Aladdin Scientific

tp@aladdinsci.com United States 57505 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532
jkinfo@jkchemical.com China 94642 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50

21411-53-0(Virginiamycin M1)Verwandte Suche:


  • C11299
  • MikamycinA, Staphylomycin
  • Antibiotic PA-114A1
  • Staphylomycin M1
  • Vernamycin A
  • VirginiaMycin M1 DISCONTINUED
  • MIKAMYCIN A
  • STAPHYLOMYCIN
  • VIRGINIAMYCINE
  • VIRGINIAMYCIN M1
  • (3R,4R,5E,10E,12E,14S)-
  • VirginiaMycin M1 (90%)
  • AVirginiaMyci
  • MikaMycin A, PristinaMycin IIA, StephyloMycin M1, StreptograMin A, Syncothrecin A, Synergistin A1, VirginiaMycin M1, VernaMycin A, 14752-2, E129A, PA 114A, 1745Z3A, 547C, Factor M
  • Ostreogrycin A
  • VirginiaMycin M1, froM StreptoMyces virginiae
  • Antibiotic PA 114A
  • Factor M
  • Factor M (antibiotic)
  • NSC 244426
  • NSC 87432
  • PA 114A
  • Pristinamycin II
  • Verginiamycin M1 Ostreogrycin A Antibiotic PA 114A NSC 244426 NSC 87432
  • Virginiamycin M1, 98%, from Streptomyces virginiae
  • 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S)-
  • Virginiamycin M1 Solution in Methanol,1000ug/ml
  • Pristinamycin IIAQ: What is Pristinamycin IIA Q: What is the CAS Number of Pristinamycin IIA Q: What is the storage condition of Pristinamycin IIA Q: What are the applications of Pristinamycin IIA
  • Pristinamycin ⅡA
  • Lepidophorin A
  • Pristinamycin IIA|||Ostreogrycin A
  • (12Z,6R,7R,8E,13E,15E,17S)-17-Hydroxy-6-isopropyl-7,15-dimethyl-32,33-dihydro-31H-5-oxa-11-aza-1(4,2)-oxazola-3(1,5)-pyrrolacycloicosaphane-8,13,15-triene-2,4,10,19-tetraone
  • Virginiamycin M1 in Methanol
  • Virginiamycin M1, 10 mM in DMSO
  • Virginiamycin M1 (Pristinamycin IIA)
  • Virginiamycin M1 (Standard)
  • Pristinamycin IIA
  • Streptogramin A
  • 21411-53-0
  • C28H35N3O7
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