3,4-Dihydroxybenzoesure
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- CAS-Nr.
- 99-50-3
- Bezeichnung:
- 3,4-Dihydroxybenzoesure
- Englisch Name:
- Protocatechuic acid
- Synonyma:
- 3,4-DIHYDROXYBENZOIC ACID;protocatechuate;Protocatechoic Acid;Hypogallic acid;3,4-Dihydroxybenzoic;PROTOCATECHUIC ACID(P);Protocatechuic aci;3,4-Dihydroxybenzoic acid,97%;Pyrocatechol-p-carboxylic acid;4-Carboxy-1,2-dihydroxybenzene
- CBNumber:
- CB3305861
- Summenformel:
- C7H6O4
- Molgewicht:
- 154.12
- MOL-Datei:
- 99-50-3.mol
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3,4-Dihydroxybenzoesure Eigenschaften
- Schmelzpunkt:
- 197-200 °C (dec.) (lit.)
- Siedepunkt:
- 237.46°C (rough estimate)
- Dichte
- 1.54
- Brechungsindex
- 1.6400 (estimate)
- FEMA
- 4430 | 3,4-DIHYDROXYBENZOIC ACID
- storage temp.
- Store below +30°C.
- L?slichkeit
- 20g/l
- pka
- 4.48(at 25℃)
- Aggregatzustand
- Fine Crystalline Powder
- Farbe
- Beige to brown
- PH
- 3.78(1 mM solution);3.25(10 mM solution);2.74(100 mM solution)
- Geruch (Odor)
- at 100.00 %. mild phenolic balsamic
- Geruchsart
- phenolic
- Wasserl?slichkeit
- Soluble in hot alcohol and ether. Slightly soluble in water.
- Sensitive
- Air Sensitive
- Merck
- 14,7894
- JECFA Number
- 2278
- BRN
- 1448841
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents, strong bases.
- Kosmetik-Inhaltsstoffe Funktionen
- SKIN PROTECTING
- InChI
- 1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
- InChIKey
- YQUVCSBJEUQKSH-UHFFFAOYSA-N
- SMILES
- OC(=O)c1ccc(O)c(O)c1
- LogP
- 1.16
- CAS Datenbank
- 99-50-3(CAS DataBase Reference)
- EPA chemische Informationen
- Protocatechuic acid (99-50-3)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
36/37/38 |
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| S-S?tze: |
26-36-37/39 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
UL0560000 |
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| HS Code |
29182990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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3,4-Dihydroxybenzoesure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white to light yellow crystal powder
Verwenden
3,4-Dihydroxybenzoic Acid is a metabolite of polyphenols such as Phloretin (P339000) and Quercetin (Q509500).
Definition
ChEBI: A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Biosynthese
Protocatechuic acid is synthesized from the intermediates of the shikimate pathway. In this case, 3-dehydroshikimate is converted to protocatechuic acid as shown in Fig.11.2. Activity measurements from mung bean seedlings, on the other hand, indicate that 3-dehydroshikimate can be converted to protocatechuic acid (Widhalm and Dudareva 2015). Protocatechuic acid (11.12) upon hydroxylation produces gal- lic acid. The enzyme catalyzing this reaction is not well understood (Muir et al.2011).
Biosynthesis of Protocatechuic Acid
Allgemeine Beschreibung
Protocatechuic acid belongs to the class of polyphenolic compounds, which can be generally isolated from the dried flower of roselle. It can serve as a potential candidate possessing anticancer property, which can be involved in suppressing the growth of human promyelocytic leukemia HL-60 cells.
Biologische Aktivit?t
Protocatechuic acid (PCA) is a dihydroxybenzoic acid phenolic compound found in many edible and medicinal plants. It is a major metabolite of antioxidant polyphenols found in green tea and demonstrates free radical scavenging capability in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assay (IC50 = 16.3 μM). It is thought to possess anti-inflammatory, antihyperglycemic, neuroprotective, and anticancer activities. Dietary administration of PCA dose dependently inhibits in vitro chemical carcinogenesis and exerts pro-apoptotic and anti-proliferative effects in different tissues. In studies of tumor cell migration and invasion using mouse melanoma B16/F10 cells, PCA at 0.1-2 mM down-regulated the Ras/Akt/NF-κB pathway by targeting RhoB activation, leading to a reduction of MMP-mediated activity.
3,4-Dihydroxybenzoesure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,4-Dihydroxybenzoesure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 804)Lieferanten
99-50-3(3,4-Dihydroxybenzoesure)Verwandte Suche:
2,3,4-Trihydroxybenzoesure
4-Hydroxybenzoesure
1-(2-Hydroxyphenyl)-3-phenylpropan-1-on
Butyl-4-hydroxybenzoat
Folsure
3-Hydroxybenzoesure
Salicyls?ure
ACETIC ACID
Methyl-4-hydroxybenzoat
3,4-Dihydroxybenzaldehyd
3,3'-(3,7,12,17-Tetramethyl-8,13-divinylporphin-2,18-diyl)di(propionsure)
Zitronensure
Glycin
ASCORBICACID
Propyl-3,4,5-trihydroxybenzoat
Dodecyl-3,4,5-trihydroxybenzoat
2,4,5-Trimethoxybenzoesure
2,5-Dihydroxybenzoes?ure
- 3,4-Dihydroxybenzoic acid >=97.0% (T)
- Carbohydroquinonic acid
- 3,4-Dihydroxybenzoic acid, >=99%
- Benzoic acid, 3,4-dihydroxy-
- PROTOCATECHUIC ACID(RG)
- 3,4-DIHYDROXYBENZOIC ACID / PROTOCATECHUIC ACID
- Protocatechuic acid ,99%
- 4-Carboxypyrocatechol
- Catechol-p-carboxylic acid
- Protocatechuic acid / 3,4-Dihydroxybenzoic acid
- Protocatechuic Acid (25 mg) (3,4-dihydroxybenzoic acid)
- 3,4-Dihydroxybenzoic acid, 97% 25GR
- 4,5-dihydroxybenzoicacid
- 3,4-DihydroxybenzoicAcid98%
- 1,2-Dihydroxybenzene-4-carboxylic Acid
- NSC 16631
- Catechol-4-carboxylic Acid
Protocatechuic Acid
Pyrocatechol-4-carboxylic Acid
- CATECHOL-4-CARBOXYLIC ACID
- 3,4-DIHYDROXYBENZOIC ACID N-HYDRATE
- 3,4-DIHYDROBENZOIC ACID
- AKOS 220-70
- RARECHEM AL BO 0347
- PROTOCATECHUIC ACID N-HYDRATE
- PROTOCATECHUIC ACID
- PYROCATECHOL-4-CARBOXYLIC ACID
- 3,4-dihydroxy-benzoicaci
- 3,4-Dihydroxybenzoic acid in stock Factory
- 3,4-Dihydroxybenzoic acid 99-50-3
- Protocatechuic acid, 99%, for synthesis
- Protocatechuic acid@100 μg/mL in AcCN
- 3,4-Dihydroxybenzoic acid USP/EP/BP
- Protocatechuic acid CAS 99-50-3 with best price
- Protocatechuic acidQ: What is
Protocatechuic acid Q: What is the CAS Number of
Protocatechuic acid Q: What is the storage condition of
Protocatechuic acid Q: What are the applications of
Protocatechuic acid
- Protocatechuic aci
- Protocatechuic acid, 4-Carboxybenzene-1,2-diol, 4-Carboxycatechol
- 3,4- twohydroxybenzoic acid/protocatechuicacid
- 3,4-Dihydroxybenzoic acid Vetec(TM) reagent grade, 97%
- Pyrocatechol-p-carboxylic acid
- 3,4-Dihydroxybenzoic acid,97%
- 3,4-Dihydroxybenzoic
- Protocatechuic acid (8CI)
- Nano-Liposomal Protocatechuic acid
- Water-Soluble Protocatechuic acid
- Protocatechuic acid-RM
- Protocatechuic acid, 10 mM in DMSO
- 3,4-Dihydroxybenzoic acid 99.5%
- Acidum protocatechuicum
- Protocatechuic acid (Standard)
- 3,4-DIHYDROXYBENZOIC ACID
- 4-Carboxy-1,2-dihydroxybenzene
- Hypogallic acid
- PROTOCATECHUIC ACID(P)
- protocatechuate
- Protocatechoic Acid
- 99-50-3
- 99-50-4
- C7H6O4xH2O
- C7H7O6
