17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA

221246-34-0

CAS-Nr.: 221246-34-0

Englisch Name:: 17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA

Synonyma:: CMLNDCUXASGBMQ-NQUQXYBYSA-N;17-trifluoromethylphenyl trinor Prostaglandin F2α;17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA;9ALPHA,11ALPHA,15S-TRIHYDROXY-17-TRIFLUOROMETHYLPHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-(3-(trifluoromethyl)phenyl)pent-1-en-1-yl)cyclopentyl)hept-5-enoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-

CBNumber:: CB3320675

Summenformel:: C24H31F3O5

Molgewicht:: 456.5

MOL-Datei:: 221246-34-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 22

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA Eigenschaften

Siedepunkt:: 593.0±50.0 °C(Predicted)

Dichte: 1.296±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

L?slichkeit: DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

pka: 4.76±0.10(Predicted)

Sicherheit

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

A number of 17-phenyl trinor prostaglandin F_2α (17-phenyl trinor PGF_2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF_2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF_2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF_2α is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol.

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20121	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Chengdu Saiousi Pharmaceutical Co., Ltd	028-64971018 18108168130		China	1781	55
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Beijing xinyanhui pharmaceutical research and development co., LTD	13969155946	1461866103@qq.com	China	16111	58
JinOu Biomedical (Nanjing) Co., Ltd.	13000000000	jinoupharma@163.com	China	11721	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24958	58

9ALPHA,11ALPHA,15S-TRIHYDROXY-17-TRIFLUOROMETHYLPHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
17-trifluoromethylphenyl trinor Prostaglandin F2α
17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA
CMLNDCUXASGBMQ-NQUQXYBYSA-N
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-(3-(trifluoromethyl)phenyl)pent-1-en-1-yl)cyclopentyl)hept-5-enoic acid
221246-34-0

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