Polaprezinc
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- CAS-Nr.
- 107667-60-7
- Englisch Name:
- Polaprezinc
- Synonyma:
- ZINC CARNOSINE;Zinc L-Carnosine;Promac;Z 103;D01611;POLAPREZINC;PepZinGI(R);Promac (tn);Polyprezine;Zn Carnosine
- CBNumber:
- CB3323797
- Summenformel:
- C9H12N4O3Zn
- Molgewicht:
- 289.61
- MOL-Datei:
- 107667-60-7.mol
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Polaprezinc Eigenschaften
- Schmelzpunkt:
- >300°C
- Siedepunkt:
- 177.5°C
- storage temp.
- Refrigerator
- L?slichkeit
- Aqueous Acid (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChI
- InChI=1/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/s3
- InChIKey
- IGXZLYMCFZHNKW-WMASNCOMNA-L
- SMILES
- [C@@H]1(C(=O)O[Zn]N1C(=O)CCN)CC1NC=NC=1 |&1:0,r|
- CAS Datenbank
- 107667-60-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Toxizit?t |
LD50 in male, female mice, rats (mg/kg): 220, 165, 405, 422 i.p.; 758, 874, >5000, >5000 s.c.; 1269, 1331, 8441, 7375 orally (Matsuda) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Polaprezinc Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Polaprezinc, a complex of zinc ion and L-carnosine, is an antiulcer agent
launched in Japan. It is effective in promoting the healing of gastric ulcers in
addition to preventing ulcer relapse. In rat studies, polaprezinc reduces the
incidence of stomach lesions induced by ethanol. No effect was seen on
ultrastructural damage or on cell proliferation and it appears that polaprezinc
combines the cytoprotective effect of zinc with the ulcer healing properties of Lcarnosine.
The in vivo antioxidative properties of polaprezinc has been suggested
to be responsible for its protective effect against gastric mucosal injury.
Recent studies revealed that polaprezinc is an activator of bone formetion and
has inhibitory effect of bone resorption. This agent is thus able to prevent the
deterioration of bone metabolism indicating its potential usefulness in the treatment
of osteoporosis. Polaprezinc has also been claimed for the prophylaxis and
treatment of alcoholic hepatopathy, viral hepatitis or other hepatopathies caused by
certain drugs, poisons and radiation.
Chemische Eigenschaften
White To Pale-Yellow Crystalline Solid
Verwenden
A novel anti-gastric ulcer agent
Polaprezinc Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Polaprezinc Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 319)Lieferanten
107667-60-7()Verwandte Suche:
- POLAPREZINC
- zinc l-carnosine complex
- zinc n-(3-aminopropionyl)histidine
- [b-Alanyl-kN-L-histidinato(2-)-kN,kO]-zinc
- b-Alanyl-L-histidinato Zinc
- Z 103
- Zinc Carnosin
- Zn Carnosine
- [-Alanyl-kN-L-histidinato(2-)-kN,kO]-zinc
- -Alanyl-L-histidinato Zinc
- carnosine, zinc-
- PepZinGI(R)
- Bis[1-(3-aminopropanoyl)-L-histidine]zinc salt
- D01611
- Polaprezinc (jan/inn)
- Promac (tn)
- Polaprezinc (Zinc Carnosine)
- Top Polaprezinc CAS NO.107667-60-7 Supplier
- Polaprezinc USP/EP/BP
- (S)-2-(3-Aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid Zinc complex
- Betacarotene EP Impurity F
- Promac
- Poly pury zinc
- L-carnosine zinc (carnosine zinc)
- Zinc Carnosine / Polaprezinc
- Piraxostat Impurity 38
- Znic-carnosine
- Polyprezine
- Beta-Alanyl-L-histidinato Zinc
- ZINC CARNOSINE
- Zinc L-Carnosine
- 107667-60-7
- C9H12N4O3Zn
- C9H14N4O3Zn
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 1
