PINOCEMBRIN
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- CAS-Nr.
- 480-39-7
- Englisch Name:
- PINOCEMBRIN
- Synonyma:
- 5,7-DIHYDROXYFLAVANONE;Picembrin;PINOCEMBRIN;pinocemberin;dihydrochrysin;Pinocembrin-RM;PINOCEMBRIN(RG);(+)-Pinocembrin;galanginflavanone;Pinocembrin (Standard)
- CBNumber:
- CB3378883
- Summenformel:
- C15H12O4
- Molgewicht:
- 256.25
- MOL-Datei:
- 480-39-7.mol
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PINOCEMBRIN Eigenschaften
- Schmelzpunkt:
- 202 °C
- Siedepunkt:
- 511.1±50.0 °C(Predicted)
- Dichte
- 1.386±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- Soluble in ethanol and methan
- Aggregatzustand
- powder
- pka
- 7.50±0.40(Predicted)
- Farbe
- White
- Major Application
- food and beverages
- InChI
- 1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1
- InChIKey
- URFCJEUYXNAHFI-ZDUSSCGKSA-N
- SMILES
- OC1=C(C(C[C@@H](C2=CC=CC=C2)O3)=O)C3=CC(O)=C1
- LogP
- 3.225 (est)
- EPA chemische Informationen
- 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2S)- (480-39-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| WGK Germany |
WGK 2 |
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| HS Code |
29329990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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PINOCEMBRIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Pinocembrin is a flavonoid that has been found in
Eucalyptus, and has diverse biological activities. It induces apoptosis in, and inhibits the migration of, SKOV3 ovarian cancer cells when used at a concentration of 200 μM. Pinocembrin (5 mg/kg) reduces lesion volume, as well as brain microglial activation and production of IL-1β, IL-6, and TNF-α in a mouse model of collagenase-induced intracerebral hemorrhage (ICH). It prevents increases in plasma and kidney malondialdehyde (MDA) levels, glomeruli lobulation, mesangial expansion, and tubule vacuolization and occlusion, and it decreases hepatic cholesterol, triglyceride, and LDL levels in a rat model of diabetic nephropathy. Pinocembrin (20 and 50 mg/kg) reduces pulmonary edema, as well as neutrophil, lymphocyte, and macrophage infiltration in a mouse model of LPS-induced lung injury.
Chemische Eigenschaften
Solid
PINOCEMBRIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
PINOCEMBRIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 278)Lieferanten
480-39-7()Verwandte Suche:
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyron
(S)-7-[[6-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-on
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyron
(S)-7-[[6-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-on
2,3-Dihydroflavon
(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on
(S)-7-[[2-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-on
(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyron
(S)-7-[[2-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-on
- 5,7-DIHYDROXY-3'4'5'-FLAVANONE
- 5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE
- PINOCEMBRIN
- (s)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4h-1-benzopyran-4-one
- 3-dihydro-5,7-dihydroxy-2-phenyl-(s)-4h-1-benzopyran-4-on
- dihydrochrysin
- galanginflavanone
- PINOCEMBRIN(RG)
- 4H-1-BENZOPYRAN-4-ONE,2,3-DIH
- PinoceMbrin, froM Pinus cerebra
- (2S)-2-Phenyl-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one
- (2S)-2α-Phenyl-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
- Picembrin
- (2S)-5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
- 5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
- Pinocembrin, 98%, from Pinus cerebra
- (2S)-5,7-Dihydroxy-2-phenylchroman-4-one
- 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2S)-
- (S)-5,7-Dihydroxy-2-Phenylchroman-4-One
- pinocemberin
- (+)-Pinocembrin
- Inhibitor,Bacterial,Autophagy,Reactive Oxygen Species,(+)-Pinocoembrin,inhibit,Pinocembrin
- Pinocembrin-RM
- Pinocembrin, 10 mM in DMSO
- Pinocembrin / Herb cardamom extract
- Pinocembrin (Standard)
- 5,7-DIHYDROXYFLAVANONE
- 480-39-7
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Flavanones
