Medroxyprogesteron
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- CAS-Nr.
- 520-85-4
- Bezeichnung:
- Medroxyprogesteron
- Englisch Name:
- MEDROXYPROGESTERONE
- Synonyma:
- (-)-Allantoin;u8840;farlutal;NSC 27408;Medoxyprogesterone;medroxyprogesteron;6-DIHYDROMEGESTROL;MEDROXYPROGESTERONE;METHYLOXYPROGESTERONE;Medroxyprogesteronebase
- CBNumber:
- CB3419654
- Summenformel:
- C22H32O3
- Molgewicht:
- 344.49
- MOL-Datei:
- 520-85-4.mol
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Medroxyprogesteron Eigenschaften
- Schmelzpunkt:
- 204-206°C
- alpha
- D25 +75° (in chloroform)
- Siedepunkt:
- 419.57°C (rough estimate)
- Dichte
- 1.0906 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.03±0.70(Predicted)
- Farbe
- White
- Merck
- 13,5817
- BRN
- 2510965
- Henry's Law Constant
- 7.6×102 mol/(m3Pa) at 25℃, HSDB (2015)
- InChI
- 1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
- InChIKey
- FRQMUZJSZHZSGN-HBNHAYAOSA-N
- SMILES
- C1[C@@]2(C)C([C@H](C[C@]3([H])[C@]2([H])CC[C@@]2(C)[C@@]3([H])CC[C@@]2(C(C)=O)O)C)=CC(=O)C1
- CAS Datenbank
- 520-85-4(CAS DataBase Reference)
- EPA chemische Informationen
- Medroxyprogesterone (520-85-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H361 |
Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Reproduktionstoxizit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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Medroxyprogesteron Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R48:Gefahr ernster Gesundheitssch?den bei l?ngerer Exposition.
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
R68:Irreversibler Schaden m?glich.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
MEDROXYPROGESTERONE is White Solid
Verwenden
MEDROXYPROGESTERONE is an orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.
Definition
ChEBI: A 3-oxo Delta4-steroid that is pregn-4-ene-3,20-dione substituted by an alpha-hydroxy group at position 17 and a methyl group at position 6.
l?uterung methode
If it contains the epi-isomer (TLC), then dissolve it in CHCl3, bubble dry HCl gas to epimerise it, evaporate and recrystallise it from chloroform. The UV has max at 241nm ( 16,150) in EtOH. The 17-acetate [71-58-9] crystallises from MeOH with m 207-208o and [] D 25 +61o (CHCl3). Its UV has max at 240nm ( 15,950) in EtOH. [Babcock et al. J Am Chem Soc 80 2904 1958, Beilstein 8 IV 2212.]
Medroxyprogesteron Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Essigs?ureanhydrid
Peroxyessigs?ure ...%
Schwefelsure
Methylmagnesiumbromid
Ethandiol
Pregnane-3,20-dione, 5,17-dihydroxy-6-methyl-, (5α,6β)-
6β-Medroxyprogesterone
3-β,17-α-Dihydroxypregn-5-en-20-on-3-acetat
6-METHYL-17A-HYDROXY PREGNENOLONE DIACETATE)
Medroxyprogesteronacetat
17-Hydroxypregn-5-en-3,20-dion cyclisch-bis(ethylen-acetal)
(5α,6α)-Epoxy-17α-hydroxy-pregnane-3,20-dione-3,20-bis(ethyleneketal)
Downstream Produkte
Medroxyprogesteron Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 190)Lieferanten
520-85-4(Medroxyprogesteron)Verwandte Suche:
- PREGN-4-ENE-3,20-DIONE,17-HYDROXY-6-ALPHA-METHYL-
- 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol
- (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- (6S,8R,9S,10R,13S,14S,17R)-17-ethanoyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- 4-Pregnen-6a-Methyl-17-ol-3,20-dione-d7
- (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-triMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
- Medroxyprogesterone acetate-13C2-d3
- 6alpha-Methyl-17alpha-hydroxypregn-4-ene-3,20-dione
- Medoxyprogesterone
- medroxyprogesterone solution,100ppm
- Medroxyprogesterone acetate Related Compound B
- farlutal
- medroxyprogesteron
- u8840
- 6α-methyl-17α-hydroxyprogesterone
- MEDROXYPROGESTERONE VETRANAL, 100 MG
- 6A-METHYL-17A-HYDROXYPROGESTERONE
- MEDROXYPROGESTERONE MM(CRM STANDARD)
- Medroxyprogesteronebase
- 17-Hydroxy-6α-methylpregn-4-ene-3,20-dione
- 17α-hydroxy-6α-methyl-4-pregnene-3,20-dione
- (6S,8R,9R,10S,13S,14R,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- 17a-Hydroxy-6a-methylprogesterone
- 17-Hydroxy-6a-methyl-pregn-4-ene-3,20-dione
- 17-Hydroxy-6a-methylpregn-4-ene-3,20dione
- 17-Hydroxy-6a-methylprogesterone
- 6a-Methyl-17a-hydroxypregn-4-ene-3,20-dione
- 6a-Methyl-17-hydroxyprogesterone
- 6a-Methyl-4-pregnen-17-a-ol-3,20-dione
- 6a-Methyl-4-pregnen-17a-ol-3,20-dione
- NSC 27408
- Pregn-4-ene-3,20-dione, 17-hydroxy-6a-methyl- (7CI, 8CI)
- Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6a)- (9CI)
- MEDROXYPROGESTERONE
- METHYLOXYPROGESTERONE
- HYDROXYMETHYLPROGESTERONE
- 17ALPHA-HYDROXY-6ALPHA-METHYL-4-PREGNENE-3,20-DIONE
- 17-hydroxy-6-methyl-20-dion(6alpha)-pren-4-ene-
- 6alpha-methyl-4-pregnen-17alpha-ol-3,20-dione
- 17ALPHA-HYDROXY-6ALPHA-METHYLPROGESTERONE
- 6-DIHYDROMEGESTROL
- 6ALPHA-METHYL-17ALPHA-HYDROXY-PROGESTERONE
- 6-ALPHA-METHYL-17-HYDROPROGESTERONE
- 6ALPHA-METHYL-5-PREGNEN-17ALPHA-OL-3,20-DIONE
- 4-PREGNEN-6-ALPHA-METHYL-17-OL-3,20-DIONE
- 17-hydroxy-6-alpha-methyl-pregn-4-ene-20-dione
- 17-hydroxy-6alpha-methyl-pregn-4-ene-20-dione
- 17-hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione
- 17-hydroxy-6alpha-methylprogesterone
- 17-hydroxy-6-methyl-20-dion(6-alpha)-pregn-4-ene-
- Medroxyprogesterone Acetate EP impurity B
- Pregn-4-ene-3,20-dione,17-hydroxy-6-methyl-, (6a)-
- Medroxyprogesterone (Medroxyprogesterone Acetate EP Impurity B)
- Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-
- Medroxyprogesterone Solution in Acetonitrile, 100μg/mL
- Medroxyprogesterone Acetate Impurity 2 (Medroxyprogesterone Acetate EP Impurity B)
- MedroxyprogesteroneQ: What is
Medroxyprogesterone Q: What is the CAS Number of
Medroxyprogesterone Q: What is the storage condition of
Medroxyprogesterone Q: What are the applications of
Medroxyprogesterone
- Medroxyprogesterone Acetate Related Compound B (17-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione) (1378023)
