Zaltoprofen
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- CAS-Nr.
- 89482-00-8
- Englisch Name:
- Zaltoprofen
- Synonyma:
- Zaltoprofeno;Peon;CN-100;Soreton;Zaltoprofen;Zaltoprofene;Zaltoprofenum;Unii-H8635ng3py;Zaltoprofen USP/EP/BP;CN 100 (antiphlogistic)
- CBNumber:
- CB3441374
- Summenformel:
- C17H14O3S
- Molgewicht:
- 298.36
- MOL-Datei:
- 89482-00-8.mol
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Zaltoprofen Eigenschaften
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Zaltoprofen Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Zaltoprofen is a potent non-steroidal antiinflammatory drug (NSAID) with analgesic
activity. In rats and mice, zaltoprofen is reported to be equipotent or superior to other NSAlDs
in bradykinin-induced pain, acetic acid-induced writhing, carrageenan-induced hyperalgesia,
and in several other experimental models of analgesia. It acts by selectively suppressing the
production of prostaglandins at the inflammatory site and not in other organs such as stomach
and kidney, therefore, has remarkably low gastric side effects that are associated with
conventional antiinflammatory agents.
Chemische Eigenschaften
Off-White to Pale Yellow Crystalline Solid
Verwenden
Anti-inflammatory activity resides in (S)-enantiomer
Synthese
The cyclization of 5-(1- cyanoethyl)-2-(phenylthio)phenylacetic acid in presence of polyphosphoric acid at 120 ℃ gives 2-(10-oxo-10,11-dihydrodibenzo[b,f ]thiepin- 2-yl)propionitrile, which is then hydrolyzed with KOH in refluxing ethanol – water to zaltoprofen.
Zaltoprofen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Zaltoprofen Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 117)Lieferanten
89482-00-8()Verwandte Suche:
Zapizolam
4,4'-[(2β,3α,5α,16β,17β)-3,17-Bis(acetoxy)androstan-2,16-diyl]bis[1,1-dimethylpiperazinium]dibromid
10,11-Dihydro-α-methyl-10-oxodibenzo[b,f]thiepin-2-essigsure
- 10,11-Dihydro-a-methyl-10-oxodibenzo[b,f]thiepin-2-acetic Acid
- 2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid
- CN-100
- Peon
- Soreton
- CN 100 (antiphlogistic)
- Dibenzo[b,f]thiepin-2-acetic acid, 10,11-dihydro-a-methyl-10-oxo- (9CI)
- (±)-10，11-Dihydro-α-methyl-10-oxodibenzo[b，f]thiepin-2-acetic acid
- Zaltoprofen
- Unii-H8635ng3py
- Zaltoprofene
- Zaltoprofene [inn-french]
- Zaltoprofeno [inn-spanish]
- Zaltoprofenum
- Zaltoprofen intermediate
- Zaltoprofen USP/EP/BP
- TIANFUCHEM--89482-00-8--Zaltoprofen
- Zaltoprofeno
- 89482-00-8
- API
- Intermediates & Fine Chemicals
- Pharmaceuticals
