Clindamycin palmitate hydrochloride
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- CAS-Nr.
- 25507-04-4
- Englisch Name:
- Clindamycin palmitate hydrochloride
- Synonyma:
- CLINDAMYCIN PALMITATE HCL;Clindmycin;Cleocin Pediatric;Clindamycin Impurity 85;Clindamycin 2-Palmitate HCl;ClindaMycin PalMitate HCl USP;Clindamycin Palmitate HCl USP37;Clindamycin Hydrochloride Palmitate;Clindamycin palmitate hydrochloride;clindamycin2’-palmitatehydrochloride
- CBNumber:
- CB3666368
- Summenformel:
- C34H64Cl2N2O6S
- Molgewicht:
- 699.85
- MOL-Datei:
- 25507-04-4.mol
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Clindamycin palmitate hydrochloride Eigenschaften
- Schmelzpunkt:
- 141-143°C
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChIKey
- GTNDZRUWKHDICY-ZLNNALEKSA-N
- SMILES
- [C@]([H])([C@]1([H])[C@@H]([C@H](O)[C@@H](OC(=O)CCCCCCCCCCCCCCC)[C@@H](SC)O1)O)([C@@H](Cl)C)NC([C@H]1N(C[C@H](CCC)C1)C)=O.Cl |&1:0,2,4,5,7,26,31,36,39,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Clindamycin palmitate hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Clindamycin palmitate is a water-soluble prodrug form of the antibiotic clindamycin . It undergoes rapid hydrolysis
in vivo to release active clindamycin. Formulations containing clindamycin palmitate have been used in the treatment of various bacterial infections.
Chemische Eigenschaften
White Solid
Verwenden
antibacterial (tuberculostatic)
Allgemeine Beschreibung
Clindamycin palmitate hydrochloride (Cleocin Pediatric) isthe hydrochloride salt of the palmitic acid ester ofcleomycin. The ester bond is to the 2-hydroxyl group of thelincosamine sugar. The ester serves as a tasteless prodrugform of the antibiotic, which hydrolyzes to clindamycin inthe plasma. The salt form confers water solubility to theester, which is available as granules for reconstitution intoan oral solution for pediatric use. Although absorption of thepalmitate is slower than that of the free base, there is littledifference in overall bioavailability of the two preparations.Reconstituted solutions of the palmitate hydrochloride arestable for 2 weeks at room temperature. Such solutionsshould not be refrigerated because thickening occurs thatmakes the preparation difficult to pour.
Clindamycin palmitate hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Clindamycin palmitate hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 224)Lieferanten
25507-04-4()Verwandte Suche:
- Clindmycin
- clindamycin2’-palmitatehydrochloride
- Methyl7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside2-hexadecanoatemonohydrochloride
- Clindamycin palmitate hydrochloride
- Clindamycin Palmitate Hydrochloride (500 mg)
- Clindamycin Palmitate Hydrochloride (500 mg)G0D334586ug/mg(an)
- ClindaMycin PalMitate HCl USP
- methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- 2-hexadecanoate-L-threo-α-D-galacto-octopyranoside,monohydrochloride
- Clindamycin Hydrochloride Palmitate
- Clindamycin 2-Palmitate HCl
- Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl] carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside 2-Hexadecanoate Monohydrochloride
- hexadecanoic acid [6-[2-chloro-1-[[(1-methyl-4-propyl-2-pyrrolidinyl)-oxomethyl]amino]propyl]-4,5-dihydroxy-2-(methylthio)-3-oxanyl] ester
- Cleocin Pediatric
- Clindamycin Palmitate Hydrochloride (USP)
- Clindmycin palmitate hydrochloride USP/EP/BP
- Clindamycin palmitate hydrochloride USP/EP/BP
- Clindamycin Palmitate Hydrochloride (1137005)
- Clindamycin Impurity 85
- CLINDAMYCIN PALMITATE HYDROCHLORIDE USP, NON-STERILE, BULK DRUG
- CLINDAMYCIN PALMITATE HYDROCHLORIDE USP (NON-STERILE DRUG SUBSTANCE)
- Clindamycin Palmitate HCl USP37
- CLINDAMYCIN PALMITATE HCL
- 25507-04-4
- C34H63CIN2O6SHCL
- C18H33ClN2O5SHClC18H34Cl2
- C34H64Cl2N2O6S
- C34H64Cl2N2O5S
- Inhibitors
- PHENYPASTEBAMIN
