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Cefcapene pivoxil

Cefcapene pivoxil Struktur
105889-45-0
CAS-Nr.
105889-45-0
Englisch Name:
Cefcapene pivoxil
Synonyma:
Fumax;S-1108;Flumax;Cefcapene Piroxil;CEFCAPENE PIVOXIL;Cefcapene Impurity 3;Cefcapene pivoxil USP/EP/BP;Cefcapene Pivoxil Impurities;Cefcapene Pivoxil See C242555;Cefcapene pivoxil Impurity 13
CBNumber:
CB3680908
Summenformel:
C23H29N5O8S2
Molgewicht:
567.64
MOL-Datei:
105889-45-0.mol

Cefcapene pivoxil Eigenschaften

Schmelzpunkt:
158-164°C
Siedepunkt:
888.4±65.0 °C(Predicted)
Dichte
1.47±0.1 g/cm3(Predicted)
L?slichkeit
DMSO, Water( warm)
Aggregatzustand
Solid
pka
11.33±0.60(Predicted)
Farbe
Off-White
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Cefcapene pivoxil Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Flomox was launched in Japan as an orally active cephalosporin for respiratory and urinary tract infections, heptatic infections, ophthalmological and otorhinolarynological infections, skinkoft tissue infections, and for use in gynacology, dentistry and oral surgery. It can be prepared by condesation of 2(Z)-(2-(t-butoxycarbonylamino) thiazol-4-yl)-2-pentenoic acid with 7-amino-3-(carbanoyloxymethyl)- 3-cephem-4-carboxylic acid pivaloyl methyl ester followed by deprotection. Flomox is highly active against a wide variety of Gram-positive and Gram-negative bacteria, except for several strains such as Pseudomonas aeruginosa and enterococci, by acting as a cell wall synthesis inhibitor (β-lactamase stability against TEM-1 type β-lactamases) and is more effective than cefaclor and cefdinir. Absorption is improved by the pivaloyloxymethyl ester group which is easily lost by deesterification during GI absorption to produce the biologically active form. The pivalic acid generated quickly conjugates with carnitine and is excreted in the urine. The drop in plasma levels of carnitine was dose dependent and returned to normal levels upon termination of treatment.

Chemische Eigenschaften

Off-White Solid

Cefcapene pivoxil Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cefcapene pivoxil Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 113)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29626 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21531 55
Xiamen AmoyChem Co., Ltd
+86-86-5926051114
sales@amoychem.com China 6361 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213
info@longyupharma.com China 2411 58
CONIER CHEM AND PHARMA LIMITED

sales@conier.com China 49906 58
career henan chemical co
+86-0371-86658258
factory@coreychem.com China 29780 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17339 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 +86-17392587031
1059@dideu.com China 9984 58
AFINE CHEMICALS LIMITED
+86-571-85134551 +86-18958018566
info@afinechem.com China 15058 58
Baoji Guokang Healthchem Co., Ltd.
+86-0917-3909592 +86-13892490616
gksales1@gk-bio.com China 9040 58

105889-45-0()Verwandte Suche:


  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester
  • Fumax
  • S-1108
  • Cefcapene Piroxil
  • Flumax
  • CEFCAPENE PIVOXIL
  • Cefcapene Pivoxil See C242555
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(2,2-diMethyl-1-oxopropoxy)Methyl ester, (6R,7R)-
  • (6R,7R)-7-[[(Z)-2-(2-amino-4-thiazolyl)-1-oxopent-2-enyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
  • Cefcapene Impurity 3
  • (6R,7R)-(pivaloyloxy)methyl7-((Z)-2-(2-aminothiazol-4-yl)pent-2-enamido)-3-((carbamoyloxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Cefcapene pivoxil USP/EP/BP
  • Cefcapene Pivoxil Impurities
  • Cefditoren pivoxilQ: What is Cefditoren pivoxil Q: What is the CAS Number of Cefditoren pivoxil Q: What is the storage condition of Cefditoren pivoxil Q: What are the applications of Cefditoren pivoxil
  • 105889-45-0 Cefcapene pivoxil
  • Cefcapene pivoxil Powder USP Standard
  • Cefcapene pivoxil Impurity 13
  • 105889-45-0
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles
  • Metabolites & Impurities
  • Sulfur & Selenium Compounds
  • Pharmaceutical intermediate
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