URSODEOXYCHOLIC-2,2,4,4-D4 ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ursodeoxycholic acid-d₄ (UDCA-d₄) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC₅₀ value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

Verwenden

Ursodeoxycholic Acid-d4 is a deuterated form of Ursodeoxcholic Acid (U850000), which is used as an anticholelithogenic. Ursodeoxcholic Acid is an epimer with Chenodiol with respect to the hydroxyl group at C7. Ursodeoxycholic Acid-d4 was used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry.

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9679	58
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18190	56
Artis Biotech Co. Ltd.	19138486554 18108108965	sales@artisbio.com	China	2404	58
Chengdu Novel Biomedical Co., Ltd.	028-85255396 18302801538	cdnovell@163.com	China	2433	58
Nanjing Haolv Biotechnology Co.,Ltd	025-84622273 17361806303	kexin.zhou@haolvbiotech.com	China	3018	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-025-85560043 17301488900	info@synzest.com	China	9286	58
Zhejiang Huida Biotech Co., LTD	0571-89903022 18679456698	zilong@hizyme.com	China	8000	58

347841-46-7()Verwandte Suche:

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• URSODEOXYCHOLIC-2,2,4,4-D4 ACID
• Ursodeoxycholic-d4 Acid
• (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• Ursodiol-d4 (Ursodeoxycholic Acid-d4)
• Ursodeoxycholic acid-[d4] (Solution)
• URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY
• URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
• Ursodeoxycholic Acid-d4 MaxSpec? Standard
• Ursodeoxycholic Acid-2,2,4,4-d4 (Major)
• (4R)-4-[(3R,5S,7S,8R,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• 2H4]-Ursodeoxycholic Acid
• Urosodeoxycholic Acid Impurity 28
• URSODEOXYCHOLICACID(2,2,4,4-D4) IN METHANOL
• *Dronedarone Impurity 37 ( Tributylamine)
• Ursodeoxycholic acid-2,2,4,4-d4
• Ursodeoxycholic Acid-d4: (3α,5β,7β)-3,7-Dihydroxycholan-24-oic-2,2,4,4-d4 acid
• D4-Ursodeoxycholic Acid
• Ursodeoxycholic acid (2,2,4,4-D?, 98%) CP 95%
• Ursodeoxycholic acid (2,2,4,4-D?, 98%) 100 μg/mL in methanol
• Ursodeoxycholic Acid-D4 (Standard)
• 347841-46-7
• C24H36D4O4
• Bile Acids - 13C & 2H