6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid
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- CAS-Nr.
- 56776-32-0
- Bezeichnung:
- 6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid
- Englisch Name:
- 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride
- Synonyma:
- Etifoxine HCl;StresaM;HOE-36801 hydrochloride;Etifoxine·hydrochloride;Etifoxine HCl (HOE-36801);NSC 163501;ANTIBIOTIC AT-125;U 42126;Etifoxine hydrochloride, 10 mM in DMSO;2-EthylaMino-6-chloro-4-Methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride;6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride;6-Chloro-N-ethyl-4-Methyl-4-phenyl-4H-3,1-benzoxazin-2-aMine Hydrochloride
- CBNumber:
- CB3883790
- Summenformel:
- C17H18Cl2N2O
- Molgewicht:
- 337.24362
- MOL-Datei:
- 56776-32-0.mol
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6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid Eigenschaften
- Schmelzpunkt:
- ND
- storage temp.
- -20°C
- L?slichkeit
- DMSO: ≥5mg/mL
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilit?t:
- Hygroscopic
- InChI
- 1S/C17H17ClN2O.ClH/c1-3-19-16-20-15-10-9-13(18)11-14(15)17(2,21-16)12-7-5-4-6-8-12;/h4-11H,3H2,1-2H3,(H,19,20);1H
- InChIKey
- SCBJXEBIMVRTJE-UHFFFAOYSA-N
- SMILES
- Cl.CCNC1=Nc2ccc(Cl)cc2C(C)(O1)c3ccccc3
6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Low Melting White Solid
Verwenden
Psychotropic agent with anxiolytic and anticonvulsant activity.
Biochem/physiol Actions
Etifoxine is an anxiolytic anticonvulsant, which promotes axonal regeneration. It binds to β2 and β3 subunits of the GABAA receptor complex, a different target site to benzodiazepines, and binds to the translocator protein (18 kDa) TSPO, formerly known as the peripheral or mitochondrial benzodiazepine receptor. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. Whereas, its anxiolytic effects involve GABAA receptors and TSPO, etifoxine′s neuroregenerative effects mainly involve TSPO.
6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 84)Lieferanten
56776-32-0(6-Chlor-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminmonohydrochlorid)Verwandte Suche:
- 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride
- Etifoxine·hydrochloride
- 6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminehydrochloride
- 2-EthylaMino-6-chloro-4-Methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride
- 6-Chloro-N-ethyl-4-Methyl-4-phenyl-4H-3,1-benzoxazin-2-aMine Hydrochloride
- StresaM
- 6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride
- HOE-36801 hydrochloride
- NSC 163501;ANTIBIOTIC AT-125;U 42126
- TBPS,Anxiolytic,Etifoxine hydrochloride,γ-Aminobutyric acid Receptor,disorder,HOE 36-801,inhibit,adjustment,Etifoxine,Inhibitor,Gamma-aminobutyric acid Receptor,GABA Receptor
- Etifoxine HCl (HOE-36801)
- Etifoxine hydrochloride, 10 mM in DMSO
- 6-chloro-n-ethyl-4-methyl-4-phenyl-4h-benzo[d][1,3]oxazin-2-amine hydrochloride
- Etifoxine HCl
- 56776-32-0
- C17H17ClN2OHCl
- Amines
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API
