6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
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- CAS-Nr.
- 1140-81-4
- Englisch Name:
- 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
- Synonyma:
- 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE;6-Acetamido-2-methyl-4-hydroxyquinoline;N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine;N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide;N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide;N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide;Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-;n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
- CBNumber:
- CB41091481
- Summenformel:
- C12H12N2O2
- Molgewicht:
- 216.24
- MOL-Datei:
- 1140-81-4.mol
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6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Eigenschaften
- Schmelzpunkt:
- >300 °C
- Siedepunkt:
- 496.0±40.0 °C(Predicted)
- Dichte
- 1.314±0.06 g/cm3(Predicted)
- L?slichkeit
- Ethyl Acetate; Toluene
- pka
- 4.29±0.40(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Yellow
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 4065, 1948
DOI: 10.1021/ja01192a031
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 18)Lieferanten
1140-81-4()Verwandte Suche:
- 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
- N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
- N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine
- N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide
- N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide
- 6-Acetamido-2-methyl-4-hydroxyquinoline
- Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-
- n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
- 1140-81-4
