1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
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- CAS-Nr.
- 192065-56-8
- Englisch Name:
- 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
- Synonyma:
- GYKI 52466 (HCl salt);GYKI 52466 hydrochloride solid;1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-5H-2,3-BENZODIAZEPINE HYDROCHLORIDE;4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride;Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1);GYKI 52466 hydrochloride,1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
- CBNumber:
- CB42129602
- Summenformel:
- C17H15N3O2HCl
- Molgewicht:
- 329.78
- MOL-Datei:
- 192065-56-8.mol
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1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride Eigenschaften
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO: soluble0.39mg/mL
- Aggregatzustand
- solid
- Farbe
- yellow
- InChI
- 1S/C17H15N3O2.ClH/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11;/h2-5,7-8H,6,9,18H2,1H3;1H
- InChIKey
- RUBSCPARMVJNKX-UHFFFAOYSA-N
- SMILES
- Cl[H].CC1=NN=C(c2ccc(N)cc2)c3cc4OCOc4cc3C1
1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
GYKI 52466 hydrochloride has been used as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor selective antagonist in cell viability assays to evaluate the specificity of kainate (KA) effect on cerebellar granule cells (CGCs). It has also been used as an AMPA blocker to study the function of glutamate in neuroadapted sindbis virus (NSV) -induced motor neuron death.
Biochem/physiol Actions
GYKI 52466 serves as an antagonist of several processes, mediated by glutamate.
1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 17)Lieferanten
- GYKI 52466 (HCl salt)
- GYKI 52466 hydrochloride,1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
- 4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride
- 1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-5H-2,3-BENZODIAZEPINE HYDROCHLORIDE
- GYKI 52466 hydrochloride solid
- Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1)
- 192065-56-8
