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HUMAN BMP-2

HUMAN BMP-2 Struktur
CAS-Nr.
Englisch Name:
HUMAN BMP-2
Synonyma:
BMP-2A;HUMAN BMP-2;HUMAN BMP-2A;BMP-2, HUMAN;RECOMBINANT HUMAN BMP-2;BONE MORPHOGENETIC PROTEIN 2;Bone morphogenetic protein 2A;HUMAN BONE MORPHOGENETIC PROTEIN-2;BONE MORPHOGENETIC PROTEINS-2, HUMAN;BONE MORPHOGENETIC PROTEIN 2 (HUMAN)
CBNumber:
CB4219446
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

HUMAN BMP-2 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
lyophilized
Biologische Quelle
human

Sicherheit

WGK Germany  WGK 3
Speicherklasse 11 - Combustible Solids

HUMAN BMP-2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

BMP-2 human has been used to study the biological role of BMP-2 on adult renal progenitor cells under in vitro and in vivo conditions.

Allgemeine Beschreibung

The functional form of BMP-2 (bone morphogenetic protein 2) is a 26kDa protein composed of two identical 114 amino-acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino-acid signal sequence for secretion, and a 259 amino-acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant human BMP-2 is a 26kDa homodimeric disulfide-linked protein consisting of two identical 115 amino acid chains.

Biochem/physiol Actions

BMP-2 (bone morphogenetic protein 2) is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. During bone repair, it controls the expression of Runt-related transcription factor 2 (Runx2) and Osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues including lung, liver, spleen, prostate, ovary, and small intestine.

HUMAN BMP-2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


HUMAN BMP-2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 88)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239
3193328036@qq.com China 29660 68
Shanghai Kanglang Biotechnology Co., Ltd. 021-61998208 18217752821
sales@klbio.cn China 9621 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10308 58
Abmole Bioscience Inc. 19821158099
sales@abmole.cn China 4494 58
Shanghai Yingxin Laboratory Equipment Co., Ltd. 021-59178156 17002132182
3146474380@qq.com China 10000 58
Vicbio Biotechnology Co., Ltd. 13621190864 13691409741
info@vicbio.com China 13100 58
Wuhan Peptide Core Biotechnology Co., Ltd 027-65317797 13667154760
1096814016@qq.com China 10711 58
Tanmo Quality Inspection Technology Co., Ltd. --
23419001name@qq.com CHINA 6043 58

  • RECOMBINANT HUMAN BMP-2
  • HUMAN BMP-2
  • HUMAN BMP-2A
  • HUMAN BONE MORPHOGENETIC PROTEIN-2
  • BONE MORPHOGENETIC PROTEIN 2
  • BONE MORPHOGENETIC PROTEIN 2 (HUMAN)
  • BONE MORPHOGENETIC PROTEINS-2, HUMAN
  • BMP-2, HUMAN
  • BMP-2A
  • Bone morphogenetic protein 2A
  • BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
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