CORTISOL-9,11,12,12-D4
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- CAS-Nr.
- 73565-87-4
- Englisch Name:
- CORTISOL-9,11,12,12-D4
- Synonyma:
- Hycort-d4;Acticort-d4;Hycortol-d4;Texacort-d4;TiMocort-d4;Cortisol-d4;D4-Cortisol;DerMacort-d4;Hydrocortal-d4;[2H4]-Cortisol
- CBNumber:
- CB4234270
- Summenformel:
- C21H26D4O5
- Molgewicht:
- 366.49
- MOL-Datei:
- 73565-87-4.mol
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CORTISOL-9,11,12,12-D4 Eigenschaften
- Schmelzpunkt:
- 211-214 °C
- Flammpunkt:
- 9℃
- storage temp.
- -20°C Freezer
- L?slichkeit
- DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly, Heated), Water
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Aussehen
- white powder
- Major Application
- clinical testing
clinical testing
- InChIKey
- JYGXADMDTFJGBT-BJJKTIQHSA-N
- SMILES
- [2H]C1([2H])[C@]([2H])(O)[C@@]2([2H])[C@@H](CCC3=CC(=O)CC[C@]23C)[C@@H]4CCC(O)(C(=O)CO)[C@@]14C
- CAS Number Unlabeled
- 50-23-7
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn,T,F |
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| R-S?tze: |
63-39/23/24/25-23/24/25-11 |
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| S-S?tze: |
36/37-45-16-7 |
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| RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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| WGK Germany |
3 |
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| Speicherklasse |
3 - Flammable liquids |
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| Hazard Classifications |
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H361 |
Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Reproduktionstoxizit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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CORTISOL-9,11,12,12-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
Hydrocortisone-d
4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson''s disease.
Chemische Eigenschaften
White Solid
Verwenden
Anti-inflammatory hormone
Allgemeine Beschreibung
Cortisol, also known as hydrocortisone, is a glucocorticoid produced by the adrenal gland. This stable labeled internal standard is suitable for quantitation of cortisol levels in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, Addison′s disease, and Sheehan′s syndrome.
CORTISOL-9,11,12,12-D4 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CORTISOL-9,11,12,12-D4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 66)Lieferanten
73565-87-4()Verwandte Suche:
- 17-Hydroxycorticosterone-9,11,12,12-d4, Cortisol-9,11,12,12-d4, Hydrocortisone-9,11,12,12-d4, Kendall's compound F (9,11,12,12-d4), Reichstein's substance M (9,11,12,12-d4), 4-Pregnene-11β,17α,21-triol-3,20-dione-d4 (9,11,12,12-d4), 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-d4 (9,11,12,12-d4)
- CORTISOL-9,11,12,12-D4
- HYDROCORTISONE (9,11,12,12-D4)
- Cortisol-D4 (9,11,12,12-D4)
- (11β)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione-d4
- 11β-Hydroxycortisone-d4
- 17-Hydroxycorticosterone-d4
- Acticort-d4
- DerMacort-d4
- Hycort-d4
- Hycortol-d4
- Hydrocortal-d4
- Pregn-4-ene-3,20-dione-d4
- Texacort-d4
- TiMocort-d4
- Cortisol-d4
- 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-D4
- Cortisol-[D4] (CertiMass solution)
- Cortisol-D4 (9,11,12, 12-D4) solution
- Cortisol-D4 (9,11,12,12-D4) solution
- Hydrocortisone-9,11,12,12-D4 solution
- Deuterated cortisol
- Deuterated hydrocortisone
- Pregn-4-ene-3,20-dione-9,11,12,12-d4,11,17,21-trihydroxy-, (11b)-
- 4-Pregnene-11β,17α,21-triol-3,20-dione-D4
- (8S,10R,11S,13S)-9,11,12,12-tetradeuterio-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- Cortisol-[d4] (Solution)
- [2H4]-Cortisol
- Hydrocortisone D4Q: What is
Hydrocortisone D4 Q: What is the CAS Number of
Hydrocortisone D4 Q: What is the storage condition of
Hydrocortisone D4 Q: What are the applications of
Hydrocortisone D4
- Hydrocortisone-d4 (Cortisol-d4)
- Pregn-4-ene-3,20-dione-9,11,12,12-d4, 11,17,21-trihydroxy-, (11β)-
- Cortisol-9,11,12,12-d?
- Cortisol-D4 (9,11,12, 12-D4) solution
- D4-Cortisol
- Cortisol (9,11,12,12-D?, 98%)
- Hydrocortisone-d4 (Hydrocortisone Acetate EP Impurity A-d4, Cortisol-d4)
- Hydrocortisone-D4 in Methanol, Concentration: 100μg/mL (Standard)
- 73565-87-4
- C21H26D4O5
- C21D4H26O5
- C21H26D4O4
- Steroids & Hormones - 13C & 2H
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Pharmaceuticals
- Steroids
