2-(Dimethylamino)-N-[11-hydroxy-3-isopropyl-5,8-dioxo-7-benzyl-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14(1),15-trien-4-yl]-3-methylpentanamide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
An alkaloid of the peptide class, this base if found in Panda oleosa Pierre. It is
best crystallized from AcOEt when it yields clusters of colourless crystals. It has
[α]
D - 103° (c 0.5, CHCI3) and gives a laevorotatory hydrochloride, m.p. 235°C
(dec.); [α]
D - 77° (c 1.0, MeOH). The presence of a hydroxyl group is shown by
the formation of the O-acetate, m.p. 30S-7°C; [α]
D - 98° (c 0.5, pyridine),
giving a hydrochloride, m.p. 280°C (dec.); [α]
D - 89° (c 1.0, MeOH). Three of
the nitrogen atoms are present as amide groups, the fourth being a dimethylamino group.
Einzelnachweise
Pais et al., Bull. Soc. Chim. Fr., 817 (1964)
2-(Dimethylamino)-N-[11-hydroxy-3-isopropyl-5,8-dioxo-7-benzyl-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14(1),15-trien-4-yl]-3-methylpentanamide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
