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nimotuzumab

nimotuzumab Struktur
828933-51-3
CAS-Nr.
828933-51-3
Englisch Name:
nimotuzumab
Synonyma:
nimotuzumab;Research Grade Nimotuzumab;Research Grade Nimotuzumab(DHB86914)
CBNumber:
CB42498825
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

nimotuzumab Eigenschaften

Sicherheit

nimotuzumab Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Overexpression of epidermal growth factor receptor (EGFR), a transmembrane receptor tyrosine kinase, is prevalent in malignant tumors of epithelial origin and is especially common in breast, head and neck, colon, and lung cancer. With EGFR overexpression, prognosis is poor due to associated tumor invasion, metastasis, enhanced angiogenesis, and resistance to chemotherapy; thus, modulation of EGFR-mediated signaling is an attractive target for intervention. Small-molecule kinase inhibitors (gefitinib and erlotinib) and a monoclonal antibody (cetuximab) specific for EGFR are in clinical evaluation, but treatment cessation due to development of severe acne-like rash is common with these EGFR antagonists. Notably, nimotuzumab, a humanized form of the murine IgG2a monoclonal antibody that has been launched in India for treatment of head and neck cancers overexpressing EGFR, demonstrates clinical efficacy devoid of the rash toxicity. .

Originator

Center for Molecular Immunology (Cuba)

Trademarks

BioMab EFGR, Theraloc

nimotuzumab Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


nimotuzumab Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 29)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000
marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 38999 58
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2110 70
Wuhan Sunrise Technology Development Co., Ltd. 27-027-83314682 13554138826
whsrtech@vip.163.com China 140 62
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
China 1490 55
SPIRO PHARMA
eric_feng1954@126.com China 9239 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9799 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994
2853530910@QQ.com China 7997 62
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340
981810490@qq.com China 1577 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10307 58

828933-51-3()Verwandte Suche:


  • nimotuzumab
  • Research Grade Nimotuzumab(DHB86914)
  • Research Grade Nimotuzumab
  • 828933-51-3
  • 828933-61-3
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