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KD 5170

KD 5170 Struktur
940943-37-3
CAS-Nr.
940943-37-3
Englisch Name:
KD 5170
Synonyma:
KD 5170;KD5170; KD-5170;KD5170, HDAC inhibitor;S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate;S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate;Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester
CBNumber:
CB42538280
Summenformel:
C20H25N3O5S2
Molgewicht:
451.56
MOL-Datei:
940943-37-3.mol

KD 5170 Eigenschaften

Siedepunkt:
637.9±65.0 °C(Predicted)
Dichte
1.310±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
≥21.2 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
Aggregatzustand
solid
pka
9.29±0.28(Predicted)
Farbe
White to yellow

Sicherheit

KD 5170 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KD 5170 is a mercaptoketone-based inhibitor of class I and II histone deacetylases (HDACs; IC50s = 20, 2,060, 75, 26, 950, 14, 85, 2,500, 150, and 18 nM for HDAC1-10, respectively). It exhibits broad spectrum antitumor activity in vitro and in vivo. KD 5170 increases the acetylation of histones and activates caspases 3, 8, and 9, leading to apoptosis in primary myeloma cells.

KD 5170 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


KD 5170 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 57)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30224 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328
sales@dogechemical.com China 4128 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850
market18@leapchem.com China 43333 58
Sichuan Biosynce Pharmatech Co., Ltd.
+8619950309693
diane@biosynce.com China 4871 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131956 58
BOC Sciences 1-631-485-4226; 16314854226
info@bocsci.com United States 9920 65
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443
yangli@happysyn.com China 2268 55

  • KD 5170
  • S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate
  • KD5170; KD-5170
  • S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate
  • Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester
  • KD5170, HDAC inhibitor
  • 940943-37-3
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