6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
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- CAS-Nr.
- 873436-91-0
- Englisch Name:
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
- Synonyma:
- CS-105;PU-H 71;NSC 750424;PU-H71 XHBr;PU-H71, >=98%;Zelavespib (PU-H71);PU-H71, 10 mM in DMSO;Zelavespib (PU-H71) ，S8039;PU-H71 Trifluoroacetic Acid;9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine
- CBNumber:
- CB42554288
- Summenformel:
- C18H21IN6O2S
- Molgewicht:
- 512.37
- MOL-Datei:
- 873436-91-0.mol
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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Eigenschaften
- Schmelzpunkt:
- >194oC (dec.)
- Siedepunkt:
- 650.6±65.0 °C(Predicted)
- Dichte
- 1.84
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 10.16±0.29(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Beige
- InChI
- InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23)
- InChIKey
- SUPVGFZUWFMATN-UHFFFAOYSA-N
- SMILES
- N1C2C(=NC=NC=2N)N(CCCNC(C)C)C=1SC1=C(I)C=C2OCOC2=C1
Sicherheit
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 148)Lieferanten
873436-91-0()Verwandte Suche:
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
- 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine
- PU-H71 Trifluoroacetic Acid
- 9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-
- NSC 750424
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine PU-H71 Trifluoroacetic Acid
- PU-H71, >=98%
- 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine
- 9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine
- PU-H 71
- CS-105
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine USP/EP/BP
- Zelavespib (PU-H71)
- PU-H71 XHBr
- PU-H71, 10 mM in DMSO
- Zelavespib (PU-H71) ，S8039
- 873436-91-0
- C18H21IN6O2S
- API
- Inhibitors
