3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol
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- CAS-Nr.
- 221352-10-9
- Englisch Name:
- 3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol
- Synonyma:
- 1,3-Dihydro-1-hydroxy-3,3-diMethyl-2,1-benzoxaborole;Tavaborole Impurity 31;3,3-Dimethylbenzo[c][1,2]oxaborol-1(3H);1-hydroxy-3,3-dimethyl-2,1-benzoxaborole;3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol;3,3-DIMETHYL-3H-BENZO[C][1,2]OXABOROL-1-OL;3,3-dimethyl-1,3-dihydro-2,1-benzoxaborol-1-ol;3,3-DIMETHYLBENZO[C][1,2]OXABOROL-1(3H)-OL(WXC01846);3,3-Dimethyl-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole
- CBNumber:
- CB42594235
- Summenformel:
- C9H11BO2
- Molgewicht:
- 161.99
- MOL-Datei:
- 221352-10-9.mol
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3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol Eigenschaften
- Siedepunkt:
- 242.5±43.0 °C(Predicted)
- Dichte
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 7.04±0.40(Predicted)
- Aussehen
- Light yellow to yellow Solid
- InChI
- InChI=1S/C9H11BO2/c1-9(2)7-5-3-4-6-8(7)10(11)12-9/h3-6,11H,1-2H3
- InChIKey
- XPHBVPSNNPMQPE-UHFFFAOYSA-N
- SMILES
- B1(O)C2=CC=CC=C2C(C)(C)O1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
To a solution of 2-(2-bromo-phenyl)-propane-2-ol (4.0 g, 18.6 mmol) in anhydrous THF (60 mL) under argon was slowly added n-butyl lithium (15 mL, 2.5 M). The mixture was stirred at -78° C for 2 h, and then triisopropylborate (5.5 mL, 24.2 mmol) was added to the mixture. The mixture was heated to room temperature and stirred for 12 h and then cooled to 0° C. Hydrochloric acid (10 mL, 1N) was added to the mixture until pH<5. The reaction system was then stirred at RT for 1 h. Until the solution was separated, the aqueous layer was extracted twice with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate, and filtered. The filtrate was concentrated under reduced pressure to afford a yellow oil. The oil was purified by chromatography (silica, EtOAc: hexanes,1:3) to afford 3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol which is a white solid.
![3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol](/NewsImg/2023-10-17/6383313715250298005052562.jpg "3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol")
3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 67)Lieferanten
- 3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol
- 3,3-Dimethylbenzo[c][1,2]oxaborol-1(3H)
- 3,3-DIMETHYL-3H-BENZO[C][1,2]OXABOROL-1-OL
- 3,3-DIMETHYLBENZO[C][1,2]OXABOROL-1(3H)-OL(WXC01846)
- 1-hydroxy-3,3-dimethyl-2,1-benzoxaborole
- 3,3-dimethyl-1,3-dihydro-2,1-benzoxaborol-1-ol
- 3,3-Dimethyl-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole
- 1,3-Dihydro-1-hydroxy-3,3-diMethyl-2,1-benzoxaborole
- Tavaborole Impurity 31
- 221352-10-9
