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Cholest-5-en-3β-ylmyristat

Cholesteryl myristate Struktur
1989-52-2
CAS-Nr.
1989-52-2
Bezeichnung:
Cholest-5-en-3β-ylmyristat
Englisch Name:
Cholesteryl myristate
Synonyma:
CM;C14:0 CE;tetradecanoate;cholanolacidester;Cholestryl myristate;CHOLESTERYL MYRISTATE;CHOLESTEROL MYRISTATE;Cholestryl myristic acid;Cholesterol Myristate >Cholesterol=tetradecanoate
CBNumber:
CB4280873
Summenformel:
C41H72O2
Molgewicht:
597.01
MOL-Datei:
1989-52-2.mol

Cholest-5-en-3β-ylmyristat Eigenschaften

Schmelzpunkt:
84 °C
Siedepunkt:
589.77°C (rough estimate)
Dichte
0.9309 (rough estimate)
Brechungsindex
1.5250 (estimate)
storage temp. 
Sealed in dry,2-8°C
L?slichkeit
Chloroform (Slightly), Hexanes (Slightly)
Aggregatzustand
A crystalline solid
Farbe
White to off-white
LogP
16.656 (est)
CAS Datenbank
1989-52-2(CAS DataBase Reference)
NIST chemische Informationen
Cholesteryl myristate(1989-52-2)
EPA chemische Informationen
Cholest-5-en-3-ol (3.beta.)-, tetradecanoate (1989-52-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36
WGK Germany  3
TSCA  TSCA listed
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P330 Mund ausspülen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Cholest-5-en-3β-ylmyristat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Cholesteryl myristate is a cholesterol ester. Levels of cholesteryl myristate are increased in the serum, liver, and aorta in rabbits fed a high-cholesterol diet and positively correlate with development of non-alcoholic fatty liver disease (NAFLD). Plasma levels of cholesteryl myristate also positively correlate with the presence of unstable atherosclerotic plaques in coronary artery disease. Cholesterol myristate has been used in the composition of lipid nanoparticles as drug carrier systems for drugs with low water solubility.

Verwenden

Cholesteryl Myristate is a natural steroid present in traditional Chinese medicine or used in tribal medicine.

Definition

ChEBI: A cholesterol ester obtained by the formal condensation of the hydroxy group of cholesterol with the carboxy group of myristic acid.

l?uterung methode

Crystallise the myristate ester from Me2CO, EtOH/EtOAc or EtOH/Et2O or n-pentanol. Purify it also by column chromatography on silica gel and eluting with MeOH then evaporating to dryness. Recrystallise it and finally, dry it in vacuo over P2O5 and store it at -20o. [Labarière et al. Analyt Chem 30 1466 1958, Malanik & Malat Anal Chim Acta 76 464 1975, Beilstein 6 III 2638].

Cholest-5-en-3β-ylmyristat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cholest-5-en-3β-ylmyristat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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1989-52-2(Cholest-5-en-3β-ylmyristat)Verwandte Suche:


  • 3β-Hydroxy-5-cholestene 3-tetradecanoate, 5-Cholesten-3β-ol 3-tetradecanoate, Cholesteryl tetradecanoate
  • Cholest-5-en-3β-ol tetradecanoate
  • Cholesterol=tetradecanoate
  • Myristic acid 3β-cholesteryl ester
  • Tetradecanoic acid 3β-cholesteryl ester
  • Cholesteryl myristate,97%,liquid crystal
  • MYRISTIC ACID CHOLESTEROL ESTER
  • (3β)-cholest-5-en-3-yltetradecanoate
  • 3β-tetradecanoyloxycholest-5-ene
  • Cholest-5-en-3-ol (3beta)-, tetradecanoate
  • Cholest-5-en-3-yl myristate
  • Cholestryl myristate
  • tetradecanoate
  • CHOLESTERYL MYRISTATE (TETRADECANOATE)
  • CHOLESTERYL MYRISTATE, LIQUID CRYSTAL 99%
  • CHOLESTERYL TETRADECANOATE
  • CHOLESTERYL TETRADODEDECANOATE
  • CHOLESTERYL MYRISTATE
  • Cholest-5-en-3beta-yl myristate
  • CHOLESTEROL MYRISTATE
  • 3BETA-HYDROXY-5-CHOLESTENE 3-TETRADECANOATE
  • [(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] tetradecanoate
  • 5-CHOLESTEN-3-BETA-OL MYRISTATE
  • 5-CHOLESTEN-3BETA-OL 3-TETRADECANOATE
  • 5-Cholesten-3β-ol 3-tetradecanoate
  • 3β-hydroxy-5-cholestene 3-tetradecanoate
  • Cholestryl myristic acid
  • Cholesteryl Tetradecanoate (Myristate)
  • Cholesteryl myristate, liquid crystal, 97%
  • Cholesterol Myristate >
  • Cholest-5-en-3-ol (3β)-, 3-tetradecanoate
  • C14:0 CE
  • (3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl tetradecanoate
  • Cholesterol myristate, >98%
  • Potassium Channel,inhibit,Endogenous Metabolite,Inhibitor,Nicotinic acetylcholine receptors,nAChR,Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,Cholesterol myristate,GABA Receptor,KcsA
  • 5-CHOLESTEN-3β-OL MYRISTATE
  • 5-Cholesten-3β-Ol 3-Tridecanoate
  • cholanolacidester
  • CM
  • 1989-52-2
  • C41H74O2
  • C41H72O2
  • BioChemical
  • Biochemicals and Reagents
  • Cholesterol and Derivatives
  • Lipids
  • Sterols
  • Steroids
  • Cholesteryl Compounds (Liquid Crystals)
  • Functional Materials
  • Liquid Crystals & Related Compounds
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