N,N'-Methantetraylbis(1-methylethylamin) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R10:Entzündlich.
R26:Sehr giftig beim Einatmen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R41:Gefahr ernster Augensch?den.
R42/43:Sensibilisierung durch Einatmen und Hautkontakt m?glich.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S38:Bei unzureichender Belüftung Atemschutzger?t anlegen.
S16:Von Zündquellen fernhalten - Nicht rauchen.

Beschreibung

Diisopropylcarbodiimide (DIC) is a clear liquid that can be easily dispensed by volume. It slowly reacts with moisture from the air, so for long term storage the bottle should be flushed with dry air or inert gas and sealed tightly. It is used in peptide chemistry as a coupling reagent. It is very toxic and caused contact dermatitis in a laboratory worker.

Chemische Eigenschaften

N,N'-Diisopropylcarbodiimide is colorless to pale yellow liquid. Insoluble in water, soluble in benzene, ethanol, ether.

Verwenden

N,N'-Diisopropylcarbodiimide is used as a reagent in synthetic organic chemistry. It serves as a chemical intermediate and as a stabilizer for Sarin (chemical weapon). It is also used in the synthesis of peptide and nucleic acid. Further, it is used as an antineoplastic and involved in the treatment of malignant melanoma and sarcomas. It is mainly used in amikacin, glutathione dehydrants, as well as in synthesis of acid anhydride, aldehyde, ketone, isocyanate; when it is used as dehydrating condensing agent, it reacts to dicyclohexylurea through short-time reaction under normal temperature.

Definition

ChEBI: A carbodiimide compound having an isopropyl substituent on both nitrogen atoms.

Allgemeine Beschreibung

N,N′-Diisopropylcarbodiimide (DIC) is a carbodiimide used as a coupling reagent in the synthesis of amides, peptides, ureas, heterocycles, and unsymmetrical carbodiimides. It is also used in the polymerization reactions as an activator.

Kontakt-Allergie

It is used in peptide chemistry as a coupling reagent. It is very toxic and causes contact dermatitis in labora- tory workers.

Synthese

Add N, N'diisopropylthiourea to the autoclave and use xylene as the solvent. The mass ratio of N, N'diisopropylthiourea to xylene solvent is 2:1. Add Sb2O4 catalyst (the amount of the catalyst is 1% of the total material), and oxygen is introduced. The temperature is increased to 115°C under a pressure of 8MPa for 4h, then lowered. Suction filtration at 15°C, decolorization, and vacuum distillation were used to obtain N, N'-Diisopropylcarbodiimide. The yield is 94.55%, and the purity is 99.55%.

N,N'-Methantetraylbis(1-methylethylamin) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N,N'-Methantetraylbis(1-methylethylamin) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Suzhou Highfine Biotech Co.,Ltd.	+86-0512-68071238 +86-13771819922	june@highfine.com	China	489	58
Shanghai Z&T Chemical Co., Ltd	+86-021-33561011 +8613818804961	Sales@ztchemical.com.cn	China	546	58
Hangzhou Verychem Science And Technology Co.Ltd	+86-86-57188162785 13606544505	lucy@verychem.com	China	1203	58
Changzhou Zechong Biopharma Co., Ltd.	+undefined18621330623	sales@zechongchem.com	China	28	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	6085	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Nantong Chem-land Co.,Ltd.	+undefined13862903883	sales@chem-land.com	China	62	58
.GZ HONESTCHEM CO.,LTD	+8615013270415	honestchemical@foxmail.com	China	248	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1056@dideu.com	China	3970	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5225	58

693-13-0(N,N'-Methantetraylbis(1-methylethylamin))Verwandte Suche:

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