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Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate Struktur
1452-94-4
CAS-Nr.
1452-94-4
Englisch Name:
Ethyl 2-chloronicotinate
Synonyma:
AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;Ethyl 2-chloronicotite;ETHYL 2-CHLORONICOTINATE;Ehtyl 2-chloronicotinate;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C
CBNumber:
CB4312224
Summenformel:
C8H8ClNO2
Molgewicht:
185.61
MOL-Datei:
1452-94-4.mol

Ethyl 2-chloronicotinate Eigenschaften

Schmelzpunkt:
68 C
Siedepunkt:
78°C (0.1 mmHg)
Dichte
1.2445 g/cm3(Temp: 25 °C)
Brechungsindex
1.5210-1.5250
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-1.32±0.10(Predicted)
Aggregatzustand
Liquid
Farbe
Colorless to Light yellow to Light orange
Major Application
pharmaceutical
InChI
InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3
InChIKey
PMIMPBYTPPRBGD-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=CC=C1C(OCC)=O
CAS Datenbank
1452-94-4(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-37/39-60-37
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29333990
Speicherklasse 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Ethyl 2-chloronicotinate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

Light yellow liquid

Verwenden

Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A

Synthese

2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Ethyl 2-chloronicotinate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 324)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+8617392709771
1097@dideu.com China 3993 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971
deasea125996@gmail.com China 2472 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3692 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
sales@frappschem.com China 880 50
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29815 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58

1452-94-4()Verwandte Suche:


  • ETHYL 2-CHLORONICOTINATE
  • ethyl 2-chloropyridine-3-carboxylate
  • 2-CHLORONICOTINIC ACID ETHYL ESTER
  • 2-Chloro-3-pyridinecarboxylic acid ethyl ester
  • 2-Chloropyridine-3-carboxylic acid ethyl ester
  • Ethyl 2-chloronicoti
  • Ethyl 2-Chloro-3-pyridinecarboxylate
  • 2-Chloronicotinic Acid Ethyl Ester Ethyl 2-Chloro-3-pyridinecarboxylate 2-Chloro-3-pyridinecarboxylic Acid Ethyl Ester
  • 2-Chloronicotinate ethyl ester
  • Ethyl 2-chloropyridine-3-carboxylate, 2-Chloro-3-(ethoxycarbonyl)pyridine
  • Flunixin Related CoMpound C
  • Ethyl 2-chloronicotinate, 99%, 99%
  • Ethyl2-chloronicotinate,98%
  • AVAC-001
  • oronicotinate
  • Flunixin Meglumine Impurity 3(Flunixin Meglumine EP Impurity C)
  • Flunixin Meglumine EP Impurity C
  • Ethyl2-Chloronicotinate>
  • Ethyl 2-Chloropyridine-3-carboxylat
  • Flunixin EP Impurity C
  • Flunixin impurity CQ: What is Flunixin impurity C Q: What is the CAS Number of Flunixin impurity C Q: What is the storage condition of Flunixin impurity C Q: What are the applications of Flunixin impurity C
  • Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631)
  • Flunixin USP Related Compound C
  • ethy-2-chloroisonicoitate
  • Flunixin Meglumine Impurity C
  • Ehtyl 2-chloronicotinate
  • Ethyl 2-chloronicotinate, 98%min
  • Ethyl 2-chloronicotite
  • Flunixin Meglumine Impurity 6
  • 1452-94-4
  • C8HBCINO2
  • pyridine series
  • Pyridines
  • Pharmaceutical Intermediates
  • Pyridine
  • Fluorobenzene
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