Dihydrokawain
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- CAS-Nr.
- 587-63-3
- Englisch Name:
- Dihydrokawain
- Synonyma:
- DIHYDROKAVAIN;MARINDININ;DIHYDROKAWAIN;dihydro-kawai;DIHYDROKAVAIN(P);Dihydrokavain-RM;7,8-DIHYDROKAWAIN;7,8-Dihydrokavain;Dihydrokavain (CRM);Dihydrokavain (Standard)
- CBNumber:
- CB4314738
- Summenformel:
- C14H16O3
- Molgewicht:
- 232.27
- MOL-Datei:
- 587-63-3.mol
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Dihydrokawain Eigenschaften
- Schmelzpunkt:
- 58-60°
- alpha
- D24 +31° (methanol)
- Siedepunkt:
- 314.44°C (rough estimate)
- Dichte
- 1.1649 (rough estimate)
- Brechungsindex
- 1.5557 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- DMF:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);21.52(Max Conc. mM)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- Optische Rotation
- [α]/D 29±2°, c = 0.5 in methanol
- BRN
- 15362
- Major Application
- food and beverages
- InChI
- InChI=1S/C14H16O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-6,10,12H,7-9H2,1H3/t12-/m0/s1
- InChIKey
- VOOYTQRREPYRIW-LBPRGKRZSA-N
- SMILES
- C1(=O)O[C@@H](CCC2=CC=CC=C2)CC(OC)=C1
- LogP
- 1.950 (est)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Dihydrokawain Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White-pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of kava-kava (Piper methysticum G. Forst).
Verwenden
(+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
Definition
ChEBI: Dihydrokavain is a member of 2-pyranones and an aromatic ether.
Application
Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.Used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
synthetische
Starting from 2,3-O-isopropylidene-D-glyceraldehyde (2) as chiral material, the naturally occurring (S)-(+)-dihydrokavain (1a) was synthesized by a procedure that involves a sonochemical Blaise reaction as the key step. The absolute configuration of (S)-(+)-dihydrokavain (1a) is demonstrated for the first time by total synthesis from a chiral source. Its opposite enantiomer, (R)-(–)-dihydrokavain (1b), was also synthesized after inversion of the chiral center in a Mitsunobu reaction.
A Total Synthesis of (+)- and (–)-Dihydrokavain with a Sonochemical Blaise Reaction as the Key Step
Dihydrokawain Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dihydrokawain Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 163)Lieferanten
587-63-3()Verwandte Suche:
- (R)-5,6-Dihydro-4-methoxy-6-phenethyl-2H-pyran-2-one
- 4-Methoxy-6-phenethyl-5,6-dihydropyran-2-one
- 4-methoxy-2-(2-phenylethyl)-2,3-dihydropyran-6-one
- (6S)-5,6-Dihydro-4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one
- (S)-(+)-7,8-Dihydrokavain
- DIHYDROKAWAIN
- MARINDININ
- 7,8-DIHYDROKAWAIN
- 5,6-dihydro-4-methoxy-6-phenethyl-2h-pyran-2-on
- DIHYDROKAVAIN(P)
- 6-dihydro-4-methoxy-6-(2-phenylethyl)-(s)-2h-pyran-2-on
- dihydro-kawai
- (6R)-4-Methoxy-6-phenethyl-5,6-dihydro-2H-pyran-2-one
- 7,8-Dihydrokavain
- Dihydrokavain (7,8-Dihydrokawain
- Dihydrokavain, 98%, from Piper methysticum Forst
- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethyl)-, (6S)-
- Dihydrokavain-RM
- Dihydrokavain, 10 mM in DMSO
- Dihydrokavain (CRM)
- (S)-4-Methoxy-6-phenethyl-5,6-dihydro-2H-pyran-2-one
- Dihydrokavain (Standard)
- DIHYDROKAVAIN
- 587-63-3
- Coumarins
