Fluxametamide
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- CAS-Nr.
- 928783-29-3
- Englisch Name:
- Fluxametamide
- Synonyma:
- 4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((methoxyamino)methylene)-2-methylbenzamide;Fluorofop;FLUXAMETAMIDE;Fluoxazole amide;Fluxametamide-002;Fluxametamide(mixture of isomers);Fluxametamide 100 μg/mL in Acetonitrile;inhibit,Inhibitor,γ-Aminobutyric acid Receptor,GABA Receptor,Fluxametamide,Gamma-aminobutyric acid Receptor;4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide;4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[(methoxyamino)methylene]-2-methylbenzamide
- CBNumber:
- CB43364536
- Summenformel:
- C20H16Cl2F3N3O3
- Molgewicht:
- 474.26
- MOL-Datei:
- 928783-29-3.mol
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Fluxametamide Eigenschaften
- Dichte
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- L?slichkeit
- DMSO : 125 mg/mL (263.57 mM);Water : < 0.1 mg/mL (insoluble)
- pka
- 11.29±0.46(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- InChI
- InChI=1S/C20H16Cl2F3N3O3/c1-11-5-12(3-4-16(11)18(29)26-10-27-30-2)17-9-19(31-28-17,20(23,24)25)13-6-14(21)8-15(22)7-13/h3-8,10H,9H2,1-2H3,(H,26,27,29)
- InChIKey
- BPFUIWLQXNPZHI-UHFFFAOYSA-N
- SMILES
- C(N=CNOC)(=O)C1=CC=C(C2CC(C3=CC(Cl)=CC(Cl)=C3)(C(F)(F)F)ON=2)C=C1C
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Fluxametamide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls).
Verwenden
Fluxametamide is a novel insecticide belongs to a class of compounds called isoxazolines, which are potent inhibitors of γ-aminobutyric acid (GABA)-, glutamate-, and glycine-gated chloride channels in insects. However, this pesticidal mode of action (MOA) does not seem to be operative in mammals as neurotoxicity was not found in either the acute or subchronic neurotoxicity studies at the limit dose.
Fluxametamide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fluxametamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 68)Lieferanten
- 4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[(methoxyamino)methylene]-2-methylbenzamide
- FLUXAMETAMIDE
- Benzamide, 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[(methoxyamino)methylene]-2-methyl-
- Fluxametamide-002
- inhibit,Inhibitor,γ-Aminobutyric acid Receptor,GABA Receptor,Fluxametamide,Gamma-aminobutyric acid Receptor
- Fluxametamide(mixture of isomers)
- Fluorofop
- Fluoxazole amide
- 4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[(Z)-methoxyiminomethyl]-2-methylbenzamide
- Fluxametamide 100 μg/mL in Acetonitrile
- 4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((methoxyamino)methylene)-2-methylbenzamide
- 928783-29-3
