NUCIFERINE
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- CAS-Nr.
- 475-83-2
- Englisch Name:
- NUCIFERINE
- Synonyma:
- nuciferin;6a;VLT 049;Nuciferi;NUCIFERINE;fettuccine;Sanjoinine;Sanjoinine E;l-nuciferine;Nuciferine-RM
- CBNumber:
- CB4384597
- Summenformel:
- C19H21NO2
- Molgewicht:
- 295.38
- MOL-Datei:
- 475-83-2.mol
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NUCIFERINE Eigenschaften
- Schmelzpunkt:
- 165.5°C
- Siedepunkt:
- 437.06°C (rough estimate)
- Dichte
- 1.1156 (rough estimate)
- Brechungsindex
- 1.5000 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- pka
- 7.87±0.20(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Optische Rotation
- [α]/D -145 to -165°, c = 0.5 in ethanol
- InChI
- InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1
- InChIKey
- ORJVQPIHKOARKV-OAHLLOKOSA-N
- SMILES
- N1(C)[C@@]2([H])C3=C(C(OC)=C(OC)C=C3CC1)C1=CC=CC=C1C2
- LogP
- 2.357 (est)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| RIDADR |
UN 1544PSN1 6.1 / PGIII |
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| HS Code |
29389090 |
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| Toxizit?t |
LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
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NUCIFERINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals
when crystallized from EtOH. It is laevorotatory, the following specific rotations
having been recorded; [α]
22D- 157.5° and - 215°. The ultraviolet spectrum has
three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and
one methylimino group are present and the alkaloid may be characterized as the
hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The
optically inactive base has been synthesized and has m.p. 136-7°C, giving a
hydrochloride in the form of small colourless prisms from H20, m.p. 258°C
(dec.).
Sicherheitsprofil
Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.
Einzelnachweise
Gulland, Haworth., J. Chern. Soc., 590 (1928)
Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940)
Arthur, Cheung., J. Chern. Soc., 2306 (1959)
Kupchan et al., Tetrahedron, 19, 227 (1963)
NUCIFERINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
NUCIFERINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 432)Lieferanten
475-83-2()Verwandte Suche:
- (-)-nucipherine
- (r)-1,2-dimethoxyaporphine
- 1,2-dimethoxy-6a-beta-aporphin
- 4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-
- Nuciferine
1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
- 5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-g)quinolin(r)-4h-dibenzo(d
- l-5,6-dimethoxyaporphine
- l-nuciferine
- NUCIFERINE
- 1,2-Dimethoxy-6aβ-aporphine
- Sanjoinine E
- (6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
- 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
- (R)-Nuciferine
- D-(-)-Nuciferine
- lotus leaf extract lotusine
- fettuccine
- Nuciferi
- Lotus leaf alkali
- NUCIFERINE USP/EP/BP
- Lotus Leaf Extract Powder Nuciferine
- (R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
- Sanjoinine
- VLT 049
- 1,2-Dimethoxy-6αβ-aporphine
- radix bupleuri P.E
- Nuciferine 475-83-2
- professional manufacturer Nuciferine 475-83-2
- Nuciferine, 98%, from Lotus Leaf
- 2%, 3%, 4%, 5%, 50%, 98% Lotus Leaf Extract Powder Nuciferine
- Lotus Leaf Extract Nuciferin
- satis indigotica fort Extract
- 6a
- NUCIFERINE (lotusleaf extract)
- Louts Leaf Extract
- Nuciferine-RM
- Nuciferine, 10 mM in DMSO
- (6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
- Nuciferine - Bio-X ?
- Extractum Nelumbinis nuciferae folium
- Nuciferine (Standard)
- nuciferin
- 475-83-2
- standardized herbal extract
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- Miscellaneous Natural Products
